Local Ancestry Prediction with PyLAE

Published: Nov. 16, 2020, 3:02 a.m.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.13.380105v1?rss=1 Authors: Smetanin, A., Moshkov, N., Tatarinova, T. V. Abstract: Summary: We developed PyLAE - a new tool for determining local ancestry along a genome using whole-genome sequencing data or high-density genotyping experiments. PyLAE can process an arbitrarily large number of ancestral populations (with or without an informative prior). Since PyLAE does not involve estimation of many parameters, it can process thousands of genomes within a day. Computational efficiency, straightforward presentation of results, and an ease of installation makes PyLAE a useful tool to study admixed populations. Availability and implementation: The source code and installation manual are available at https://github.com/smetam/pylae. Copy rights belong to original authors. Visit the link for more info