echolocatoR: an automated end-to-end statistical and functional genomic fine-mapping pipeline

Published: Oct. 23, 2020, 1:02 a.m.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.22.351221v1?rss=1 Authors: Schilder, B. M., Humphrey, J., Raj, T. Abstract: echolocatoR integrates a diverse suite of statistical and functional fine-mapping tools in order to identify, test enrichment in, and visualize high-confidence causal consensus variants in any phenotype. It requires minimal input from users (a summary statistics file), can be run in a single R function, and provides extensive access to relevant datasets (e.g. reference linkage disequilibrium (LD) panels, quantitative trait loci (QTL) datasets, genome-wide annotations, cell type-specific epigenomics, thereby enabling rapid, robust and scalable end-to-end fine-mapping investigations. Copy rights belong to original authors. Visit the link for more info