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b'The current thoughts around LDL cholesterol center on the fact that there is no scenario in which high LDL numbers could occur in healthy individuals. Traditionally, the belief is high levels of LDL can lead to a greater risk of cardiovascular disease regardless of metabolic health. Today\\u2019s guest is here to share his hypothesis and research on how higher cholesterol levels in metabolically fit individuals could be a physiological response rather than a pathological response that can lead to disease.\\xa0\\nToday on The Dhru Purohit Show, Dhru sits down with Dave Feldman to discuss high levels of LDL in metabolically healthy individuals. Dave shares the current research on high LDL and cardiovascular disease in individuals eating a ketogenic diet. He also shares his personal approach to focusing on metabolic health and the key markers critical to overall health. Dave discusses the process and findings of the Oreo experiment conducted by his colleague and explains why this experiment further proves their hypothesis on how LDL particles move through the body.\\xa0\\nDave Feldman is a software and platform engineer, entrepreneur, and founder of the Citizen Science Foundation. Through a series of self-experiments and partnering with formal researchers, he has since published the "Lipid Energy Model," which may explain this phenomenon.\\xa0\\nIn this episode, Dhru and Dave dive into (audio version / Apple Subscriber version):\\n\\nDave\\u2019s hypothesis on LDL (00:24 /00:24)\\n\\nRethinking our approach to high LDL (2:17 / 2:17)\\xa0\\n\\nThe research on high LDL and cardiovascular disease (10:00 / 6:48)\\xa0\\n\\nThe Oreo experiment and what it shows about fat adaptation (17:23 / 13:45)\\n\\nThe pushback to lean mass hyper responder (27:36 / 24:15)\\xa0\\n\\nSoft plaque versus hard plaque and the risk of cardiovascular disease (37:50 / 35:04)\\xa0\\n\\nDave\\u2019s personal approach in focusing on overall metabolic health (51:42 / 48:30)\\xa0\\n\\nFasting Insulin and Vitamin D (59:33 / 53:45)\\xa0\\n\\nEndothelial health and cardiovascular health (1:03:28 / 57:45)\\xa0\\n\\nThe vegan\\u2019s twin study and the correlation to LDL (1:21:17 / 1:15:49)\\n\\nDhru\\u2019s experience (1:32:17 / 1:26:36)\\xa0\\n\\n\\nAlso mentioned in this episode:\\n\\nCitizen Science Foundation\\xa0\\n\\nOreo Cookie Treatment\\n\\nNicolas Norwitz, PhD Twitter\\xa0\\n\\n\\nThis episode is brought to you by LMNT, Momentous, and Lumebox.\\xa0\\nRight now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today.\\nOptimize your Omega-3 levels by choosing a quality fish oil made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order.\\xa0\\nLumebox is offering my community $260 off their FDA-approved portable Red Light device!\\xa0That\'s over 50% off! Go to thelumebox.com/dhru and get your Red Light device.\\n Hosted on Acast. See acast.com/privacy for more information.\\nLearn more about your ad choices. Visit megaphone.fm/adchoices'