Ohio State vs. Indiana game preview: Game picks, over-unders and best defense OSU has faced

Published: Oct. 22, 2021, 4:30 a.m.

b"On this Friday game preview, Doug Lesmerises, Nathan Baird and Stephen Means look at just how good the Indiana defense is that Ohio State will face in Bloomington on Saturday night. The six defenses left for Ohio State in the regular season are all ranked higher than any of the six defenses the Buckeyes have faced so far.\\nWill Indiana's top cornerbacks play? Would Hoosiers linebacker Micah McFadden be the best player on Ohio State's defense? If Indiana stopped Michigan State running back Kenneth Walker III last week, will OSU back TreVeyon Henderson be controlled this week?\\nThe Indiana offense isn't very good, but the defense should give the Buckeyes their best test yet. So should you take Ohio State as a 21-point favorite or not? Also, there's a brief discussion on giving up on your dreams as a kid.\\nThanks for listening to another Buckeye Talk from cleveland.com.\\n See acast.com/privacy for privacy and opt-out information.\\nLearn more about your ad choices. Visit megaphone.fm/adchoices"