Podcasts Science

647 episodes

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Podcasts

Sex Differences in MRI-Based Metrics of Glioma Invasion and Brain Mechanics

Published: Nov. 22, 2020, 3:03 a.m.
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Listed in: Science

Three-dimensional interrelationship between osteocyte network and forming mineral during human bone remodeling

Published: Nov. 21, 2020, 10:03 a.m.
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Coarse-grained modeling of mitochondrial metabolism enables subcellular flux inference from fluorescence lifetime imaging microscopy

Published: Nov. 21, 2020, 9:02 a.m.
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TRPV channel OCR-2 is distributed along C. elegans chemosensory cilia by diffusion in a local interplay with intraflagellar transport

Published: Nov. 20, 2020, 11:01 p.m.
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AI-Driven Multiscale Simulations Illuminate Mechanisms of SARS-CoV-2 Spike Dynamics

Published: Nov. 20, 2020, 10:02 p.m.
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Adherent cell remodeling on micropatterns is modulated by Piezo1 channels

Published: Nov. 20, 2020, 3:03 p.m.
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Optimal density of biological cells

Published: Nov. 20, 2020, 4:03 a.m.
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Biological autoluminescence for assessing oxidative processes in yeast cell cultures

Published: Nov. 20, 2020, 4:03 a.m.
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The role of alpha-helix on the structure-targeting drug design of amyloidogenic proteins

Published: Nov. 20, 2020, 3:07 a.m.
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How a Hemicarcerand Incarcerates Guests at Room Temperature Decoded with Modular Simulations

Published: Nov. 20, 2020, 3:06 a.m.
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AMPGAN v2: Machine Learning Guided Discovery of Anti-Microbial Peptides

Published: Nov. 20, 2020, 2:05 a.m.
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Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity

Published: Nov. 20, 2020, 1:03 a.m.
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Mechanical Efficiency Investigation of an ankle-assisted robot for human walking with a backpack-load

Published: Nov. 20, 2020, 1:03 a.m.
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Fast Vesicle Fusion Mediated by Hydrophobic Dipeptides

Published: Nov. 20, 2020, 12:02 a.m.
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Binding of dsRNA by D. melanogaster Dicer-2 is substrate-dependent and regulated by Loquacious-PD

Published: Nov. 19, 2020, 5:02 a.m.
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Do the loops in N-SH2 binding cleft truly serve as allosteric switch in SHP2 activation?

Published: Nov. 19, 2020, 5:02 a.m.
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Ultrafast Brownian-ratchet mechanism for protein translocation by a AAA+ machine

Published: Nov. 19, 2020, 4:03 a.m.
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Raman microscopy-based quantification of the physical properties of intracellular lipids

Published: Nov. 19, 2020, 3:03 a.m.
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The structural mechanism underlying the antithetic effect of homologous RND1 and RhoD GTPases in plexin regulation

Published: Nov. 19, 2020, 3:03 a.m.
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Biochemical and Biophysical Characterization of the dsDNA packaging motor from the Lactococcus lactis bacteriophage asccphi28

Published: Nov. 18, 2020, 7:02 p.m.
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A generalised mechano-kinetic model for use in multiscale simulation protocols.

Published: Nov. 18, 2020, 7:02 p.m.
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ATP hydrolysis coordinates the activities of two motors in a dimeric chromatin remodeling enzyme

Published: Nov. 18, 2020, 10:02 a.m.
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Structural Basis of Complex Formation Between Mitochondrial Anion Channel VDAC1 and Hexokinase-II

Published: Nov. 18, 2020, 8:02 a.m.
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Effect of cholesterol on permeability of carbon dioxide across lipid membranes

Published: Nov. 17, 2020, 7:01 p.m.
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Dynamics of vesicle reshaping and scission under osmotic shocks

Published: Nov. 17, 2020, 6:03 p.m.
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Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer's disease

Published: Nov. 17, 2020, 2:03 a.m.
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Perphenazine-macrocycle conjugates divert Aβ42 towards non-toxic aggregates by monomer sequestration.

Published: Nov. 17, 2020, 2:03 a.m.
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Active Participation of Membrane Lipids in Inhibition of Multidrug Transporter P-Glycoprotein

Published: Nov. 16, 2020, 9:02 p.m.
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Rapid HIV-1 capsid interaction screening using fluorescence fluctuationspectroscopy

Published: Nov. 16, 2020, 3:02 p.m.
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α-Synuclein emerges as a potent regulator of VDAC-facilitated calcium transport

Published: Nov. 16, 2020, 3:03 a.m.
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Disclosing the actual efficiency of G-quadruplex DNA-disrupting small molecules

Published: Nov. 16, 2020, 3:03 a.m.
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Machine learning aided top-down protein identification on a microfluidic platform

Published: Nov. 16, 2020, 3:03 a.m.
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Design of intrinsically disordered proteins that undergo phase transitions with lower critical solution temperatures

Published: Nov. 15, 2020, 11:04 a.m.
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Single-femtosecond atomic-resolution observation of a protein traversing a conical intersection

Published: Nov. 15, 2020, 11:04 a.m.
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Molecular and spectroscopic characterization of green and red cyanine fluorophores from the Alexa Fluor and AF series

Published: Nov. 15, 2020, 9:02 a.m.
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X-ray Irradiation activates immune response in human T-lymphocytes by eliciting a Ca2+ signaling cascade

Published: Nov. 15, 2020, 9:02 a.m.
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Dissecting the role of glutamine in seeding peptide aggregation.

Published: Nov. 15, 2020, 5:05 a.m.
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The solution structures of higher-order human telomere G-quadruplex multimers

Published: Nov. 14, 2020, 10:02 a.m.
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Encoding multiple virtual signals in DNA barcodes with single-molecule FRET

Published: Nov. 13, 2020, 1:02 a.m.
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Biophysical characterization of two commercially available preparations of the drug containing Escherichia coli L-Asparaginase 2

Published: Nov. 12, 2020, 10:05 p.m.
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Biased re-orientation in the chemotaxis of peritrichous bacteria

Published: Nov. 12, 2020, 10:04 p.m.
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Bifurcations and mutation hot-spots in the SARS-CoV-2 spike protein

Published: Nov. 12, 2020, 3:02 a.m.
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Massive X-ray screening reveals two allosteric drug binding sites of SARS-CoV-2 main protease

Published: Nov. 12, 2020, 3:02 a.m.
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Building blocks of protein structures - Physics meets Biology

Published: Nov. 11, 2020, 9:05 p.m.
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Bacterial pore-forming proteins induce non-monotonic dynamics due to lipid ejection and crowding

Published: Nov. 11, 2020, 6:02 a.m.
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Water-mediated interactions determine helix formation of peptides in open nanotubes

Published: Nov. 11, 2020, 5:02 a.m.
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Swimming, fast and slow: strategy and survival ofbacterial predators in response to chemical cues

Published: Nov. 11, 2020, 4:02 a.m.
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Dengue virus protease activity modulated by dynamics of protease cofactor

Published: Nov. 11, 2020, 4:02 a.m.
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A Structural Ensemble of a Tau-Microtubule Complex Reveals Regulatory Tau Phosphorylation and Acetylation Mechanisms

Published: Nov. 10, 2020, 6:03 p.m.
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Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super-relaxed state: multiscale measurements and computational modeling

Published: Nov. 10, 2020, 6:03 p.m.
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Insights into G-Quadruplex-Hemin Dynamics Using Atomistic Simulations: Implications for Reactivity and Folding

Published: Nov. 10, 2020, 6:03 p.m.
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Beneficent and maleficent effects of cations on bufadienolide binding to Na+,K+-ATPase

Published: Nov. 10, 2020, 4:03 p.m.
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Towards Targeting the Disordered SARS-CoV-2 Nsp2 C-terminal Region: Partial Structure and Dampened Mobility Revealed by NMR Spectroscopy

Published: Nov. 9, 2020, 10:02 p.m.
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Retardation of folding rates of substrate proteins in the nanocage of GroEL

Published: Nov. 9, 2020, 10:02 p.m.
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Effects of sea ice and wind speed on Phytoplankton spring bloom in Central and Southern Baltic Sea

Published: Nov. 9, 2020, 7:02 a.m.
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What Markov state models can and cannot do: Correlation versus path-based observables in protein folding models

Published: Nov. 9, 2020, 5:02 a.m.
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The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds

Published: Nov. 9, 2020, 4:02 a.m.
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Turing's diffusive threshold in random reaction-diffusion systems

Published: Nov. 9, 2020, 3:02 a.m.
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3D nanoscale analysis of bone healing around degrading Mg implants studied by X-ray scattering tensor tomography

Published: Nov. 9, 2020, 3:02 a.m.
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Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy

Published: Nov. 9, 2020, 3:02 a.m.
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Spatiotemporal model of cellular mechanotransduction via Rho and YAP

Published: Nov. 9, 2020, 12:02 a.m.
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PyBindingCurve, simulation and curve fitting to complex binding systems at equilibrium.

Published: Nov. 8, 2020, 7:04 p.m.
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Selection of start codon during mRNA scanning in eukaryotic translation initiation

Published: Nov. 8, 2020, 12:02 p.m.
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Engineered Tissue Interfaces for in vitro and in vivo Bioengineering

Published: Nov. 8, 2020, 12:02 p.m.
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The correlation between antiviral drug, immune response and HIV viral load

Published: Nov. 8, 2020, 12:02 p.m.
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Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM

Published: Nov. 8, 2020, 3:02 a.m.
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DNA G-quadruplexes for native mass spectrometry in potassium: a database of validated structures in electrospray-compatible conditions

Published: Nov. 7, 2020, 10:02 a.m.
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An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding

Published: Nov. 7, 2020, 9:02 a.m.
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Synergy and allostery in ligand binding by HIV-1 Nef

Published: Nov. 5, 2020, 7:01 a.m.
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Viscophobic turning regulates microalgae transport in viscosity gradients

Published: Nov. 5, 2020, 5:02 a.m.
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A Minimal, Adaptive Binning Scheme for Weighted Ensemble Simulations

Published: Nov. 5, 2020, 4:02 a.m.
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Nucleoid associated proteins and their effect on E. coli chromosome

Published: Nov. 5, 2020, 3:02 a.m.
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Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins

Published: Nov. 5, 2020, 3:01 a.m.
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Cryo-EM structure of a proton-activated chloride channel TMEM206

Published: Nov. 5, 2020, 2:02 a.m.
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Finite-size transitions in complex membranes

Published: Nov. 5, 2020, 2:02 a.m.
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The fluid dynamics of collective vortex structures of plant-animal worms

Published: Nov. 5, 2020, 1:04 a.m.
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Mechanistic inferences from analysis of measurements of protein phase transitions in live cells

Published: Nov. 5, 2020, 1:04 a.m.
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Performance of deep learning restoration methods for the extraction of particle dynamics in noisy microscopy image sequences

Published: Nov. 5, 2020, 12:03 a.m.
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Ligand-induced motions in pentameric ligand-gated ion channels revealed by EPR spectroscopy

Published: Nov. 5, 2020, 12:03 a.m.
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Shock and Detonation Waves at an Interface and the Collision of Action Potentials

Published: Nov. 4, 2020, 7:02 p.m.
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Statistical Physics of DNA melting: Unveiling the artificial corrections for self-complementary sequences

Published: Nov. 4, 2020, 3:01 p.m.
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Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination

Published: Nov. 4, 2020, 4:02 a.m.
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Cryo-EM analysis of human mitochondrial Hsp90 in multiple tetrameric states

Published: Nov. 4, 2020, 4:02 a.m.
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Resolving the step size in condensin-driven DNA loop extrusion identifies ATP binding as the step-generating process

Published: Nov. 4, 2020, 2:02 a.m.
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RESTORING CONNEXIN-36 FUNCTION IN DIABETOGENIC ENVIRONMENTS PRECLUDES MOUSE AND HUMAN ISLET DYSFUNCTION

Published: Nov. 3, 2020, 8:02 p.m.
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Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis

Published: Nov. 3, 2020, 6:02 p.m.
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Kinetic model of small RNA-mediated regulation suggests that a small RNA can regulate co-transcriptionally

Published: Nov. 3, 2020, 6:02 p.m.
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The Hsc70 Disaggregation Machinery RemovesMonomer Units Directly from α-Synuclein FibrilEnds

Published: Nov. 3, 2020, 5:02 a.m.
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Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics

Published: Nov. 2, 2020, 4:02 a.m.
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A biophysical limit for quorum sensing in biofilms

Published: Nov. 2, 2020, 2:04 a.m.
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Transient K+ current explains cross-species differences in the effects of myofibroblasts on myocytes

Published: Nov. 2, 2020, 2:04 a.m.
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Characterization of structural and energetic differences between conformations of the SARS-CoV-2 spike protein

Published: Nov. 2, 2020, 2:04 a.m.
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Structural basis for repurpose and design of nucleoside drugs for treating COVID-19

Published: Nov. 2, 2020, 12:02 a.m.
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Molecular dynamics and in silico mutagenesis on the reversible inhibitor-bound SARS-CoV-2 Main Protease complexes reveal the role of lateral pocket in enhancing the ligand affinity

Published: Nov. 1, 2020, 10:02 p.m.
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Mechanism of ligand recognition by human ACE2 receptor

Published: Nov. 1, 2020, 10:02 p.m.
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MINSTED fluorescence localization and nanoscopy

Published: Nov. 1, 2020, 1:02 p.m.
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Fast inactivation of Na+ current in rat adrenal chromaffin cells involves two independent inactivation pathways

Published: Nov. 1, 2020, 12:03 p.m.
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Triblock copolymer micelle model of spherical paraspeckles

Published: Nov. 1, 2020, 6:02 a.m.
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Nav1.3 and fibroblast growth factor homologous factor 14 are primary determinants of the TTX-sensitive sodium current in mouse adrenal chromaffin cells

Published: Oct. 31, 2020, 11:02 p.m.
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Mechanism of RNA recognition by a Musashi RNA-binding protein

Published: Oct. 31, 2020, 11:02 p.m.
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Moleculewise semi-grand canonical ensembles

Published: Oct. 30, 2020, 9:01 p.m.
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Signature molecular changes in the skeletal muscle of hindlimb unloaded mice

Published: Oct. 30, 2020, 9:01 p.m.
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Binding of Ca2+-Independent C2 Domains to Lipid Membranes: a Multi-Scale Molecular Dynamics Study

Published: Oct. 30, 2020, 7:02 p.m.
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Allosteric regulation in CRISPRCas1-Cas2 protospacer acquisition mediated by DNA in association with Cas2

Published: Oct. 30, 2020, 3:03 p.m.
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Combined fluorescence, optical diffraction tomography and Brillouin microscopy

Published: Oct. 30, 2020, 3:03 p.m.
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Altering CLC stoichiometry by reducing non-polar side-chains at the dimerization interface

Published: Oct. 30, 2020, 3:03 p.m.
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Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails

Published: Oct. 30, 2020, 3:01 a.m.
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Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain

Published: Oct. 29, 2020, 9:01 p.m.
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Liquid condensates increase potency of amyloid fibril inhibitors

Published: Oct. 29, 2020, 7:03 p.m.
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Heat hypersensitivity of ryanodine receptor type 1 mutants implicated in malignant hyperthermia

Published: Oct. 29, 2020, 5:04 p.m.
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Absolute measurement of cellular activities using photochromic single-fluorophore biosensors

Published: Oct. 29, 2020, 5:03 p.m.
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The propofol binding sites of prokaryotic voltage-gated sodium channels

Published: Oct. 29, 2020, 5:03 p.m.
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Modeling the Opening SARS-CoV-2 Spike: an Investigation of its Dynamic Electro-Geometric Properties

Published: Oct. 29, 2020, 4:02 a.m.
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Real-Time Multi-Angle Projection Imaging of Biological Dynamics

Published: Oct. 29, 2020, 4:02 a.m.
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Sodium channel toxin-resistance mutations do not govern batrachotoxin (BTX) autoresistance in poison birds and frogs

Published: Oct. 29, 2020, 4:02 a.m.
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A Mechanistic Basis for Inhibition of TREK-2 K2P Channels by Norfluoxetine

Published: Oct. 29, 2020, 3:02 a.m.
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Nature of active forces in tissues: how contractile cells can form extensile monolayers

Published: Oct. 28, 2020, 6:03 p.m.
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Small subpopulations of β-cells do not drive islet oscillatory dynamics via gap junction communication

Published: Oct. 28, 2020, 5:02 p.m.
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Direct Measurement of Unsteady Microscale Stokes Flow Using Optically Driven Microspheres

Published: Oct. 28, 2020, 6:02 a.m.
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Structural insights into the cooperative interaction of the intrinsically disordered co-activator TIF2 with retinoic acid receptor heterodimer (RXRRAR)

Published: Oct. 28, 2020, 5:02 a.m.
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Phosphorothioate substitutions in RNA structure studied by molecular dynamics simulations, QMMM calculations and NMR experiments

Published: Oct. 28, 2020, 5:02 a.m.
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Fast volumetric mapping of human brain slices

Published: Oct. 27, 2020, 11:01 p.m.
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DNA-loop extruding SMC complexes can traverse one another in vivo

Published: Oct. 27, 2020, 7:03 p.m.
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Deep-learning based denoising and reconstruction of super-resolution structured illumination microscopy images

Published: Oct. 27, 2020, 7:03 p.m.
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Negative durotaxis: cell movement toward softer environments

Published: Oct. 27, 2020, 4:02 a.m.
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Binding Mode of SARS-CoV2 Fusion Peptide to Human Cellular Membrane

Published: Oct. 27, 2020, 4:02 a.m.
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Tumorigenic epithelial clusters are less sensitive to moderate osmotic stresses due to low amounts of junctional E-cadherin

Published: Oct. 27, 2020, 3:02 a.m.
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Machine learning models for predicting protein condensate formation from sequence determinants and embeddings

Published: Oct. 26, 2020, 9:02 p.m.
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Multi-dimensional digital bioassay platform based on an air-sealed femtoliter reactor array device

Published: Oct. 26, 2020, 2:02 p.m.
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Structural basis of rotavirus RNA chaperone displacement and RNA annealing

Published: Oct. 26, 2020, 2:02 p.m.
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Reversible coating of cells with synthetic polymers for mechanochemical regulation of cell adhesion

Published: Oct. 26, 2020, 2:01 p.m.
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Not so optimal: The evolution of mutual information in potassium voltage-gated channels

Published: Oct. 26, 2020, 7:01 a.m.
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Roughness and dynamics of proliferating cell fronts as a probe of cell-cell interactions

Published: Oct. 26, 2020, 5:02 a.m.
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Dinucleotides as simple models of the base stacking-unstacking component of DNA 'breathing' mechanisms

Published: Oct. 26, 2020, 4:03 a.m.
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Deep learning enables fast and dense single-molecule localization with high accuracy

Published: Oct. 26, 2020, 4:03 a.m.
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Mechanically Induced Integrin Ligation Mediates Intracellular Calcium Signaling with Single Pulsating Cavitation Bubbles

Published: Oct. 25, 2020, 6:03 p.m.
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Bayesian inference: The comprehensive approach to analyzing single-molecule experiments

Published: Oct. 25, 2020, 6:03 p.m.
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Fitting quantum machine learning potentials to experimental free energy data: Predicting tautomer ratios in solution

Published: Oct. 25, 2020, 12:03 p.m.
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Fast and exact single and double mutation-response scanning of proteins

Published: Oct. 25, 2020, 12:03 p.m.
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Quantitative phase microscopy enables precise and efficient determination of biomolecular condensate composition

Published: Oct. 25, 2020, 3:02 a.m.
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Towards designing globular antimicrobial peptide mimics: role of polar functional groups in biomimetic ternary antimicrobial polymers

Published: Oct. 24, 2020, 1:02 p.m.
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Mesoscale phase separation of chromatin in the nucleus

Published: Oct. 24, 2020, 11:02 a.m.
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Emergent robustness of bacterial quorum sensing in fluid flow

Published: Oct. 24, 2020, 11:02 a.m.
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Following the footprints of variability during filopodia growth

Published: Oct. 23, 2020, 10:02 p.m.
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How subtle changes in 3D structure can create large changes in transcription

Published: Oct. 23, 2020, 10:02 p.m.
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The mechanism of motor inhibition by microtubule-associated proteins

Published: Oct. 23, 2020, 10:02 p.m.
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Lactate transport at the uteroplacental unit- A theoretical study

Published: Oct. 23, 2020, 7:02 a.m.
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Physical biology of cell-substrate interactions under cyclic stretch

Published: Oct. 23, 2020, 12:04 a.m.
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Analysis of SARS-CoV-2 ORF3a structure reveals chloride binding sites

Published: Oct. 22, 2020, 10:02 p.m.
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Membrane Shape Remodeling by Protein Crowding

Published: Oct. 22, 2020, 9:01 a.m.
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Resonance Raman spectra for the in-situ identification of bacteria strains and their inactivation

Published: Oct. 22, 2020, 5:02 a.m.
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The main activatory and tension-sensitive transitions occur within Prozac sensitive down-states of the potassium selective TREK-2 channel

Published: Oct. 22, 2020, 5:02 a.m.
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Mechanistic picture for chemo-mechanical couplings in a bacterial proton-coupled oligopeptide transporter from Streptococcus thermophilus

Published: Oct. 22, 2020, 4:03 a.m.
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Glycolysis Inhibition Regulates Endothelial Junctions by Perturbing Actin and Focal Adhesions

Published: Oct. 22, 2020, 4:03 a.m.
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Variations of intracellular density during the cell cycle arises from tip-growth regulation in fission yeast

Published: Oct. 22, 2020, 3:03 a.m.
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Two-photon microscopy at >500 volumessecond

Published: Oct. 22, 2020, 2:04 a.m.
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Asymmetry in Histone Rotation in Forced Unwrapping and Force Quench Rewrapping in a Nucleosome

Published: Oct. 21, 2020, 9:02 p.m.
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Positive allosteric modulators of lecithin:cholesterol acyltransferase adjust the orientation of the membrane-binding domain and alter its spatial free energy profile

Published: Oct. 21, 2020, 8:02 p.m.
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The collapse of the spindle following ablation in S. pombe is mediated by microtubules and the motor protein dynein

Published: Oct. 21, 2020, 8:02 p.m.
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High throughput measurements of BMPBMP receptors interactions using bio-layer interferometry

Published: Oct. 21, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Targeted modulation of protein liquid-liquid phase separation by evolution of amino-acid sequence

Published: Oct. 21, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

The Mechanical Roles of Chaperons

Published: Oct. 21, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

Ribosome Exit Tunnel Electrostatics

Published: Oct. 21, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

The domain-within-domain packing of euchromatin can be described as multiplicative cascades

Published: Oct. 21, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

Nanoscopic Structural Fluctuations of Disassembling Microtubules Revealed by Label-Free Super-Resolution Microscopy

Published: Oct. 21, 2020, 8:01 a.m.
Duration: N/A

Listed in: Science

Viral surface geometry shapes influenza and coronavirus spike evolution

Published: Oct. 20, 2020, 3:01 a.m.
Duration: N/A

Listed in: Science

High resolution and high throughput bacteria separation from blood using elasto-inertial microfluidics

Published: Oct. 19, 2020, 10:01 p.m.
Duration: N/A

Listed in: Science

High-resolution cryo-EM structure of photosystem II: Effects of electron beam damage

Published: Oct. 19, 2020, 10:01 p.m.
Duration: N/A

Listed in: Science

Tautomerization constraints the accuracy of codon-anticodon decoding

Published: Oct. 19, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Markov State Models and NMR Uncover an Overlooked Allosteric Loop in p53

Published: Oct. 19, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Real-Time Observation of Structure and Dynamics during the Liquid-to-Solid Transition of FUS LC

Published: Oct. 19, 2020, 12:02 a.m.
Duration: N/A

Listed in: Science

Evolution of structural dynamics in bilobed proteins

Published: Oct. 19, 2020, 12:02 a.m.
Duration: N/A

Listed in: Science

Changes in the three-dimensional microscale topography of human skin with aging impact its mechanical and tribological behavior

Published: Oct. 18, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Molecular mechanism of SARS-CoV-2 inactivation by temperature

Published: Oct. 18, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Elucidation and control of low and high active populations of alkaline phosphatase molecules for quantitative digital bioassay

Published: Oct. 18, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Structure, Dynamics, Receptor Binding, and Antibody Binding of Fully-glycosylated Full-length SARS-CoV-2 Spike Protein in a Viral Membrane

Published: Oct. 18, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Role of TNF-α among inflammatory molecules secreted by injured astrocytes in the modulation of in vitro neuronal networks

Published: Oct. 16, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Avoiding tensional equilibrium in cells migrating on a matrix with cell-scale stiffness-heterogeneity

Published: Oct. 16, 2020, 6:02 p.m.
Duration: N/A

Listed in: Science

Computational and experimental analyses of mitotic chromosome formation pathways in fission yeast

Published: Oct. 16, 2020, 6:02 p.m.
Duration: N/A

Listed in: Science

On the global attractors in one mathematical model of antiviral immunity

Published: Oct. 16, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Force transduction creates long-ranged coupling in ribosomes stalled by arrest peptides

Published: Oct. 16, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Overview of the SAMPL6 pKa Challenge: Evaluating small molecule microscopic and macroscopic pKa predictions

Published: Oct. 15, 2020, 6:03 a.m.
Duration: N/A

Listed in: Science

Exploring the pH-dependent structure-dynamics function relationship of human renin

Published: Oct. 15, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

High-Resolution Single-Molecule FRET via DNA eXchange (FRET X)

Published: Oct. 15, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Ultrafast phasor-based hyperspectral snapshot microscopy for biomedical imaging

Published: Oct. 15, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Hebbian learning with elasticity explains how the spontaneous motor tempo affects music performance synchronization

Published: Oct. 15, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

SiGMoiD: A superstatistical generative model for binary data

Published: Oct. 15, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Transfer function for YAPTAZ nuclear translocation revealed through spatial systems modeling

Published: Oct. 15, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Climbing up and down binding landscapes: a high-throughput study of mutational effects in homologous protein-protein complexes

Published: Oct. 14, 2020, 9:02 p.m.
Duration: N/A

Listed in: Science

A Multisite Model of Allosterism for the Adenosine A1 Receptor

Published: Oct. 14, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

PIP2 promotes conformation-specific dimerization of the EphA2 membrane region

Published: Oct. 14, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

Protein-DNA target search relies on Quantum Walk

Published: Oct. 14, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

Agonist efficiency estimated from concentration-response curves

Published: Oct. 14, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

Mechanisms of scaffold-mediated microcompartment assembly and size-control

Published: Oct. 14, 2020, 8:02 a.m.
Duration: N/A

Listed in: Science

Ensemble epistasis: thermodynamic origins of non-additivity between mutations

Published: Oct. 14, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

3D test sample for the calibration and quality control of super-resolution and confocal microscopes

Published: Oct. 14, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Structural stability of SARS-CoV-2 degrades with temperature

Published: Oct. 14, 2020, 12:03 a.m.
Duration: N/A

Listed in: Science

Discovery of deformation mechanisms and constitutive response of soft material surrogates of biological tissue by full-field characterization and data-driven variational system identification

Published: Oct. 14, 2020, 12:03 a.m.
Duration: N/A

Listed in: Science

Multi-Modal Single-Molecule Imaging with Continuously Controlled Spectral-resolution (CoCoS) Microscopy

Published: Oct. 13, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

How Euglena gracilis swims: flow field reconstruction and analysis

Published: Oct. 12, 2020, 4:02 p.m.
Duration: N/A

Listed in: Science

Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2

Published: Oct. 12, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

The effect of salt on the dynamics of CoV-2 RBD at ACE2

Published: Oct. 12, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

Optical Tweezer Stretching of Miniature Coarse-Grained Red Blood Cells

Published: Oct. 12, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

The geometric determinants of programmed antibody migration and binding on multi-antigen substrates

Published: Oct. 12, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Optimal design of adaptively sampled NMR experiments for measurement of methyl group dynamics with application to a ribosome-nascent chain complex

Published: Oct. 12, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast fusion of the readily releasable pool of vesicles

Published: Oct. 12, 2020, 3:02 a.m.
Duration: N/A

Listed in: Science

Defocus-dependent Thon-ring fading

Published: Oct. 12, 2020, 3:02 a.m.
Duration: N/A

Listed in: Science

Enhanced Loading of Paclitaxel in Cationic Liposomes by Replacement of Oleoyl with Linoleoyl Lipid Tails with Benefits in Cancer Therapeutics from In Vitro Studies

Published: Oct. 12, 2020, 3:02 a.m.
Duration: N/A

Listed in: Science

Light transport modeling in highly complex tissues using implicit mesh-based Monte Carlo algorithm

Published: Oct. 12, 2020, 2:04 a.m.
Duration: N/A

Listed in: Science

Structure of the ancestral TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium

Published: Oct. 12, 2020, 2:04 a.m.
Duration: N/A

Listed in: Science

Finding Pathogenic nsSNP's and their structural effect on COPS2 using Molecular Dynamic Approach

Published: Oct. 12, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1S2 junction

Published: Oct. 12, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Structural investigation of ACE2 dependent disassembly of the trimeric SARS-CoV-2 Spike glycoprotein

Published: Oct. 12, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Structure Specific Neuro-toxicity of α-Synuclein Oligomer

Published: Oct. 11, 2020, 4:03 a.m.
Duration: N/A

Listed in: Science

Efficacy of information transmission in cellular communication

Published: Oct. 11, 2020, 4:03 a.m.
Duration: N/A

Listed in: Science

Extended and dynamic linker histone-DNA interactions control chromatosome compaction

Published: Oct. 10, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Simulation of FUS protein condensates with an adapted coarse-grained model

Published: Oct. 10, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Extra-cellular Matrix in cell aggregates is a proxy to mechanically control cell proliferation and motility

Published: Oct. 9, 2020, 3:02 p.m.
Duration: N/A

Listed in: Science

Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphogenesis

Published: Oct. 9, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Role of cell polarity dynamics and motility in pattern formation due to contact dependent signalling

Published: Oct. 9, 2020, 3:03 a.m.
Duration: N/A

Listed in: Science

HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

Published: Oct. 9, 2020, 3:03 a.m.
Duration: N/A

Listed in: Science

ATP regulates TDP-43 pathogenesis by specifically binding to an inhibitory component of a delicate network controlling LLPS

Published: Oct. 8, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Protein diffusion on membrane domes, tubes and pearling structures

Published: Oct. 8, 2020, 3:02 a.m.
Duration: N/A

Listed in: Science

Effects of High Magnetic Fields on Diffusion of Biologically Active Molecules

Published: Oct. 8, 2020, 3:02 a.m.
Duration: N/A

Listed in: Science

Fabrication and electromechanical characterization of free-standing asymmetric membranes

Published: Oct. 8, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Redesigning OmpA Loops Using Canonical Outer Membrane Protein Loop Structures

Published: Oct. 8, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Single-cell tracking reveals super-spreading cells with high persistence in invasive brain cancer

Published: Oct. 7, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Proton wires mediate the optical signal for ArcLight-type Genetically Encoded Voltage Indicators

Published: Oct. 7, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Glycan-induced protein dynamics in human norovirus P dimers depend on virus strain and deamidation status

Published: Oct. 7, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Dimerization of a membrane transporter is driven by differential energetics of lipid solvation of dissociated and associated states

Published: Oct. 7, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope tag insertion

Published: Oct. 7, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Differential expression of proteins in human prostate cancer tissues probed by MALDI imaging mass spectrometry

Published: Oct. 7, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Steric Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface

Published: Oct. 7, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Ready-to-use nanopore platform for the detection of any DNARNA oligo at attomole range using an Osmium tagged complementary probe.

Published: Oct. 6, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

The guidance and adhesion protein FLRT2 dimerizes in cis via dual Small-X3-Small transmembrane motifs

Published: Oct. 6, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding

Published: Oct. 6, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Cryo-EM reveals the dynamic interplay between mitochondrial Hsp90 and SdhB folding intermediates

Published: Oct. 6, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Single depolymerizing and transport kinesins stabilize microtubule ends

Published: Oct. 5, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Implementing and assessing an alchemical method for calculating protein-protein binding free energy

Published: Oct. 4, 2020, 10:03 a.m.
Duration: N/A

Listed in: Science

Axon Diameter Measurements using Diffusion MRI are Infeasible

Published: Oct. 3, 2020, 9:03 a.m.
Duration: N/A

Listed in: Science

A hybrid mesh and voxel based Monte Carlo algorithm for accurate and efficient photon transport modeling in complex bio-tissues

Published: Oct. 3, 2020, 9:03 a.m.
Duration: N/A

Listed in: Science

Physical modelling of multivalent interactions in the nuclear pore complex

Published: Oct. 3, 2020, 9:03 a.m.
Duration: N/A

Listed in: Science

Lipid interactions of an actinoporin pore-forming oligomer

Published: Oct. 3, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Concentration Sensing in Crowded Environments

Published: Oct. 3, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Simulating digital micromirror devices for patterning coherent excitation light in structured illumination microscopy

Published: Oct. 3, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture

Published: Oct. 3, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Amyloidogenic core of a human {lambda}-III immunoglobulin light chain fibril and their germline variants probed by MAS solid state NMR

Published: Oct. 2, 2020, 9:03 a.m.
Duration: N/A

Listed in: Science

The neuronal associations of respiratory-volume variability in the resting state

Published: Oct. 2, 2020, 8:02 a.m.
Duration: N/A

Listed in: Science

Dwarf open reading frame (DWORF) peptide is a direct activator of the sarcoplasmic reticulum calcium pump SERCA.

Published: Oct. 2, 2020, 8:02 a.m.
Duration: N/A

Listed in: Science

Proton-Dependent Inhibition, Inverted Voltage Activation, and Slow Gating of CLC-0 Chloride Channel

Published: Oct. 2, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

A Generative Approach toward Precision Antimicrobial Peptide Design

Published: Oct. 2, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Human hypertrophic cardiomyopathy mutation R712L suppresses the working stroke of cardiac myosin and can be rescued by omecamtiv mecarbil

Published: Oct. 2, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion

Published: Oct. 2, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Adaptive conformational restraints for interactive model rebuilding in Cartesian and torsion space

Published: Oct. 1, 2020, 10:02 p.m.
Duration: N/A

Listed in: Science

Determination of Bacterial Surface Charge Density Via Saturation of Adsorbed Ions

Published: Oct. 1, 2020, 10:02 p.m.
Duration: N/A

Listed in: Science

Fluorescence-free quantification of proteinnucleic-acid binding through single-molecule kinetic locking

Published: Oct. 1, 2020, 7:03 p.m.
Duration: N/A

Listed in: Science

Could network structures generated with simple rules imposed on a cubic lattice reproduce the structural descriptors of globular proteins?

Published: Oct. 1, 2020, 8:02 a.m.
Duration: N/A

Listed in: Science

Cryo-electron tomography of the herpesvirus procapsid reveals interactions of the portal with the scaffold and a shift on maturation

Published: Oct. 1, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Pathway dynamics can delineate the sources of transcriptional noise in gene expression

Published: Sept. 30, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

PYMEVisualize: an open-source tool for exploring 3D super-resolution data

Published: Sept. 30, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

A super-resolution protocol to correlate structural underpinnings of fast second-messenger signalling in primary cell types

Published: Sept. 30, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

A real-time, transient kinetic study of Drosophila melanogaster Dicer-2 elucidates mechanism of termini-dependent cleavage of dsRNA.

Published: Sept. 30, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

Assessment of Software Methods for Estimating Protein-Protein Relative Binding Affinities

Published: Sept. 30, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Subunit epsilon of E. coli F1Fo ATP synthase attenuates enzyme activity by modulating central stalk flexibility

Published: Sept. 30, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Malaria parasites differentially sense environmental elasticity during transmission

Published: Sept. 30, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

The genotype-phenotype landscape of an allosteric protein

Published: Sept. 30, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Enumerating High Numbers of Fluorophores from Photobleaching Experiments: a Bayesian Nonparametrics Approach

Published: Sept. 30, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes

Published: Sept. 30, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Structural and dynamical heterogeneity of water trapped inside Na+-pumping KR2 rhodopsin in the dark state

Published: Sept. 29, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Non-equilibrium Living Polymers

Published: Sept. 29, 2020, 5:01 p.m.
Duration: N/A

Listed in: Science

Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM

Published: Sept. 29, 2020, 3:02 p.m.
Duration: N/A

Listed in: Science

Interconversion of unexpected thiol states affects stability, structure and dynamics in engineered antibody for site-specific conjugation

Published: Sept. 29, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

The extent of protein hydration dictates the preference for heterogeneous or homogeneous nucleation generating either parallel or antiparallel β-sheet α-synuclein aggregates

Published: Sept. 29, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Pinching the cortex of live cells reveals thickness instabilities caused by Myosin II motors

Published: Sept. 29, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

EPI Distortion Correction is Easy and Useful, and You Should Use It: A case study with toddler data

Published: Sept. 29, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

pyTFM: A tool for Traction Force and Monolayer Stress Microscopy

Published: Sept. 28, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Understanding the origins of loss of protein function by analyzing the effects of thousands of variants on activity and abundance

Published: Sept. 28, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Exploring dynamics and network analysis of spike glycoprotein of SARS-COV-2

Published: Sept. 28, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Fluorescence-detection size-exclusion chromatography utilizing nanobody technology for expression screening of membrane proteins

Published: Sept. 28, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

A Tethered Ligand Assay to Probe the SARS-CoV-2 ACE2 Interaction under Constant Force

Published: Sept. 28, 2020, 2:03 a.m.
Duration: N/A

Listed in: Science

Sequence-dependent mechanics of collagen reflect its structural and functional organization

Published: Sept. 28, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Structural characterization of an RNA bound antiterminator protein reveal a successive binding mode

Published: Sept. 28, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP

Published: Sept. 28, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Estimating Multiple Latencies in the Auditory System from Auditory Steady-State Responses on a Single EEG Channel

Published: Sept. 28, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Control of helical navigation by three-dimensional flagellar beating

Published: Sept. 27, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Measuring Protein Insertion Areas in Lipid Monolayers by Fluorescence Correlation Spectroscopy

Published: Sept. 26, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Single-molecule light-sheet microscopy with local nanopipette delivery

Published: Sept. 26, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Requirements for FisB-mediated membrane fission during sporulation

Published: Sept. 26, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Structural asymmetry along protein sequences and co-translational folding

Published: Sept. 26, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

The C-terminal domain of transcription factor RfaH: Folding, fold switching and energy landscape

Published: Sept. 26, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Coexisting lipid phases alter lipid dynamics and sort on nanoscale membrane curvature

Published: Sept. 25, 2020, 11:02 p.m.
Duration: N/A

Listed in: Science

Tissue Dynamics Spectroscopic Imaging: Functional Imaging of Heterogeneous Cancer Tissue

Published: Sept. 25, 2020, 7:02 p.m.
Duration: N/A

Listed in: Science

Dynamic Mechanochemical feedback between curvedmembranes and BAR protein self-organization

Published: Sept. 25, 2020, 10:01 a.m.
Duration: N/A

Listed in: Science

Integrated structure-function dataset reveals key mechanisms underlying photochromic fluorescent proteins

Published: Sept. 25, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

The Origin of Conductive-Pulse Sensing Inside a Nanopore and the Role of Electro-Hydrodynamics

Published: Sept. 25, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Intrinsic and extrinsic noise are distinguishable in a synthesis - export - degradation model of mRNA production

Published: Sept. 25, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Sequence dependence of biomolecular phase separation

Published: Sept. 25, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Surface condensation of a pioneer transcription factor on DNA

Published: Sept. 25, 2020, 12:04 a.m.
Duration: N/A

Listed in: Science

Super-relaxed state of myosin in human skeletal muscle is fiber-type dependent

Published: Sept. 25, 2020, 12:03 a.m.
Duration: N/A

Listed in: Science

Supercoiling Enhances DNA Mobility by Reducing Threadings and Entanglements

Published: Sept. 24, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

Functionalized bead assay to measure 3-dimensional traction forces during T-cell activation

Published: Sept. 24, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

A joint reaction coordinate for computing the free energy landscape of pore nucleation and pore expansion in lipid membranes

Published: Sept. 24, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Across kingdom biased CYP-mediated metabolism via small-molecule ligands docking on P450 oxidoreductase

Published: Sept. 24, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

TopoStats - an automated tracing program for AFM images

Published: Sept. 24, 2020, 3:01 a.m.
Duration: N/A

Listed in: Science

A second PI(4,5)P2 binding site determines PI(4,5)P2 sensitivity of the tubby domain

Published: Sept. 23, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

The His-tag as a decoy modulating preferred orientation in cryoEM

Published: Sept. 23, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

Kinetics of self-assembly of inclusions due to lipid membrane thickness interactions

Published: Sept. 23, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Virus-host interactions shape viral dispersal giving rise to distinct classes of travelling waves in spatial expansions

Published: Sept. 23, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

A Highly Conserved 310-Helix Within the Kinesin Motor Domain is Critical for Kinesin Function and Human Health.

Published: Sept. 22, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Single-molecule interaction microscopy reveals antibody binding kinetics

Published: Sept. 22, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Single-molecule FRET dynamics of molecular motors in an ABEL Trap

Published: Sept. 22, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Structural Mechanism Underlying Ligand Binding and Activation of PPARγ

Published: Sept. 22, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Structural basis for conformational equilibrium of the catalytic spliceosome

Published: Sept. 22, 2020, 5:03 a.m.
Duration: N/A

Listed in: Science

The interplay between asymmetric and symmetric DNA loop extrusion

Published: Sept. 22, 2020, 5:03 a.m.
Duration: N/A

Listed in: Science

The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform

Published: Sept. 22, 2020, 5:03 a.m.
Duration: N/A

Listed in: Science

Electron flow through NDH-1 complexes is the major driver of cyclic electron flow-dependent proton pumping in cyanobacteria

Published: Sept. 22, 2020, 4:01 a.m.
Duration: N/A

Listed in: Science

Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution

Published: Sept. 22, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

The transmembrane domain of DWORF activates SERCA directly; P15 and W22 residues are essential.

Published: Sept. 21, 2020, 5:01 p.m.
Duration: N/A

Listed in: Science

Functional and structural characterization of interactions between opposite subunits in HCN pacemaker channels

Published: Sept. 21, 2020, 3:01 a.m.
Duration: N/A

Listed in: Science

Cryo-EM structure of S-Trimer, a subunit vaccine candidate for COVID-19

Published: Sept. 21, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

The Dynamic Influence of Linker Histone Saturation within the Poly-Nucleosome Array

Published: Sept. 21, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Ligand Modulation of the Conformational Dynamics of the A2A Adenosine Receptor Revealed by Single-Molecule Fluorescence

Published: Sept. 20, 2020, 6:03 a.m.
Duration: N/A

Listed in: Science

The regulatory function of the AAA4 ATPase domain of cytoplasmic dynein

Published: Sept. 20, 2020, 6:03 a.m.
Duration: N/A

Listed in: Science

Coarse-grained implicit solvent lipid force field with a compatible resolution to the Cα protein representation

Published: Sept. 20, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Filopodia rotate and coil by actively generating twist in their actin shaft

Published: Sept. 20, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells

Published: Sept. 20, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

A structured viral RNA uses molecular mimicry and conformational dynamics to coordinate multiple functions

Published: Sept. 20, 2020, 1:04 a.m.
Duration: N/A

Listed in: Science

Capillary forces drive pioneer transcription factor-mediated DNA condensation

Published: Sept. 20, 2020, 1:04 a.m.
Duration: N/A

Listed in: Science

Challenges in solving structures from radiation-damaged tomograms of protein nanocrystals assessed by simulation

Published: Sept. 20, 2020, 1:03 a.m.
Duration: N/A

Listed in: Science

Structural determinants of calcium binding beyond the EF-hand binding site: A study of alpha parvalbumins

Published: Sept. 20, 2020, 12:04 a.m.
Duration: N/A

Listed in: Science

Nanomechanical phenotypes in cMyBP-C mutants that cause hypertrophic cardiomyopathy

Published: Sept. 19, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Targeting G-quadruplex Forming Sequences with Cas9

Published: Sept. 19, 2020, 5:03 a.m.
Duration: N/A

Listed in: Science

MicroED structure of lipid-embedded mammalian mitochondrial voltage dependent anion channel

Published: Sept. 19, 2020, 5:03 a.m.
Duration: N/A

Listed in: Science

WASP: A software package for correctly characterizing the topological development of ribbon structures

Published: Sept. 18, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Evolution of the Analytical Scattering Model of Live Escherichia Coli

Published: Sept. 18, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Reaction Pathway Sampling and Free Energy Analyses for Multimeric Protein Complex Disassembly with Employing Hybrid Configuration Bias Monte CarloMolecular Dynamics Simulation

Published: Sept. 17, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Short Peptides as Predictors for the Structure of Polyarginine Sequences in Disordered Proteins.

Published: Sept. 17, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Extreme Fuzzy Association of an Intrinsically Disordered Protein with Acidic Membranes

Published: Sept. 17, 2020, 2:03 a.m.
Duration: N/A

Listed in: Science

Topography, spike dynamics and nanomechanics of individual native SARS-CoV-2 virions

Published: Sept. 17, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

The flexibility of ACE2 in the context of SARS-CoV-2 infection

Published: Sept. 16, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

A torsion-based rheometer for measuring viscoelastic material properties

Published: Sept. 16, 2020, 4:02 p.m.
Duration: N/A

Listed in: Science

All protein aggregates will thermodynamically order

Published: Sept. 16, 2020, 4:02 p.m.
Duration: N/A

Listed in: Science

IM30 IDPs form a membrane protective carpet upon super-complex disassembly

Published: Sept. 16, 2020, 4:02 p.m.
Duration: N/A

Listed in: Science

Cryo-EM structure of yeast 90S preribosome at 3.4 Angstrom resolution

Published: Sept. 16, 2020, 4:02 p.m.
Duration: N/A

Listed in: Science

Understanding the photophysics and structural organization of photosynthetic proteins using model lipid membranes assembled from natural plant thylakoids

Published: Sept. 16, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

High-resolution Crystal Structures of Transient Intermediates in the Phytochrome Photocycle

Published: Sept. 16, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Single-molecule measurements reveal that PARP1 condenses DNA by loop formation

Published: Sept. 15, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

Controlling T cells shape, mechanics and activation by micropatterning.

Published: Sept. 15, 2020, 7:02 p.m.
Duration: N/A

Listed in: Science

Intracellular Optical Doppler Phenotypes of Chemosensitivity in Human Epithelial Ovarian Cancer

Published: Sept. 15, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum

Published: Sept. 15, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Stationary Ca2+ nanodomains in the presence of buffers with two binding sites

Published: Sept. 15, 2020, 1:01 p.m.
Duration: N/A

Listed in: Science

W-RESP: Well-Restrained Electrostatic Potential Derived Charges. Revisiting the Charge Derivation Model.

Published: Sept. 14, 2020, 10:01 p.m.
Duration: N/A

Listed in: Science

Synchronous and Asynchronous Response in Dynamically Perturbed Proteins

Published: Sept. 14, 2020, 10:01 p.m.
Duration: N/A

Listed in: Science

Single-molecule spectroscopy reveals dynamic allostery mediated by the substrate-binding domain of a AAA+ machine

Published: Sept. 14, 2020, 5:03 p.m.
Duration: N/A

Listed in: Science

High yield preparation of outer-membrane protein efflux pumps by in vitro refolding is concentration dependent

Published: Sept. 14, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

A high-affinity calmodulin-binding site in the CyaA toxin translocation domain is essential for invasion into eukaryotic cells

Published: Sept. 14, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Actin cytoskeletal and focal adhesion organisation in U2OS cells on polymer nanostructures

Published: Sept. 14, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

Published: Sept. 14, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

TIN2 facilitates TRF1-mediated trans- and cis-interactions on physiologically relevant long telomeric DNA

Published: Sept. 13, 2020, 12:01 p.m.
Duration: N/A

Listed in: Science

Circadian rhythms of early afterdepolarizations and ventricular arrhythmias in a cardiomyocyte model

Published: Sept. 13, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing

Published: Sept. 13, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

GR chaperone cycle mechanism revealed by cryo-EM: reactivation of GR by the GR:Hsp90:p23 client-maturation complex

Published: Sept. 13, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

Exploring the binding of resveratrol to promoter DNA sequence d(CCAATTGG)2 using biophysical studies

Published: Sept. 12, 2020, 4:02 p.m.
Duration: N/A

Listed in: Science

Optimizing Mitochondrial Maintenance in Extended Neuronal Projections

Published: Sept. 12, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Ab-initio determination of the shape of membrane proteins in a nanodisc

Published: Sept. 12, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

S494 O-glycosylation site on the SARS-COV-2 RBD Affects the Virus Affinity to ACE2 and its Infectivity; A Molecular Dynamics Study

Published: Sept. 12, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

Heterogeneous aggregation of amyloid-β 42 from single-molecule spectroscopy

Published: Sept. 11, 2020, 5:04 p.m.
Duration: N/A

Listed in: Science

Long time-scale study of von Willebrand factor multimers in extensional flow

Published: Sept. 11, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

Structural and dynamic characterization of the C-terminal tail of ErbB2: disordered but not random

Published: Sept. 11, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

Computational 4D-OCM for label-free imaging of collective cell invasion and force-mediated deformations in collagen

Published: Sept. 11, 2020, 11:02 a.m.
Duration: N/A

Listed in: Science

Mechanistic basis for motor-driven membrane constriction by dynamin

Published: Sept. 11, 2020, 10:01 a.m.
Duration: N/A

Listed in: Science

Stability of Human Serum Amyloid A Fibrils

Published: Sept. 11, 2020, 10:01 a.m.
Duration: N/A

Listed in: Science

Vital Insights into Prokaryotic Genome Compaction by Nucleoid-Associated Protein (NAP) and Illustration of DNA Flexure Angles at Single Molecule Resolution

Published: Sept. 11, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Refinement of a Cryo-EM Structure of hERG: Bridging Structure and Function

Published: Sept. 11, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

A comparative survey of betacoronavirus strain molecular dynamics identifies key ACE2 binding sites

Published: Sept. 11, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

SARS-CoV-2 NSP1 C-terminal region (residues 130-180) is an intrinsically disordered region

Published: Sept. 11, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

Automated deep lineage tree analysis using a Bayesian single cell tracking approach

Published: Sept. 10, 2020, 5:03 p.m.
Duration: N/A

Listed in: Science

Mechanical principles governing the shapes of dendritic spines

Published: Sept. 10, 2020, 2:01 p.m.
Duration: N/A

Listed in: Science

Phase separation of tunable biomolecular condensates predicted by an interacting particle model

Published: Sept. 10, 2020, 2:01 p.m.
Duration: N/A

Listed in: Science

DBFOLD: An efficient algorithm for computing folding pathways of complex proteins

Published: Sept. 10, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Pro-drug peptide and its metabolites disrupt amyloid fibrils by destabilizing salt bridge interaction and planar beta-sheet topology

Published: Sept. 10, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Molecular basis for SARS-CoV-2 spike affinity for human ACE2 receptor

Published: Sept. 10, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Different force fields give rise to different amyloid aggregation pathways in molecular dynamics simulations

Published: Sept. 10, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Topological Assembly of a Deployable Hoberman Flight Ring from DNA

Published: Sept. 10, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Inhibitor binding influences the protonation states of histidines in SARS-CoV-2 main protease

Published: Sept. 10, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

De Novo Design of Allosteric Control into Rotary Motor V1-ATPase by Restoring Lost Function

Published: Sept. 9, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Label-free imaging and classification of live P. falciparum

Published: Sept. 9, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Near-Physiological-Temperature Serial Femtosecond X-ray Crystallography Reveals Novel Conformations of SARS-CoV-2 Main Protease Active Site for Improved Drug Repurposing

Published: Sept. 9, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Live cell PNA labelling enables erasable fluorescence imaging of membrane proteins

Published: Sept. 9, 2020, 4:01 a.m.
Duration: N/A

Listed in: Science

Vimentin intermediate filaments mediate cell shape on visco-elastic substrates

Published: Sept. 8, 2020, 5:01 p.m.
Duration: N/A

Listed in: Science

Emergence of behavior in a self-organized living matter network

Published: Sept. 8, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

Label-free and Multimodal Second Harmonic Generation Light Sheet Microscopy

Published: Sept. 8, 2020, 1:01 p.m.
Duration: N/A

Listed in: Science

Characterizing mechanics of membrane tether from relaxation curve obtained by optical tweezers

Published: Sept. 7, 2020, 9:02 p.m.
Duration: N/A

Listed in: Science

Cholesterol in membranes facilitates aggregation of amyloid beta protein at physiologically low concentrations

Published: Sept. 7, 2020, 9:02 p.m.
Duration: N/A

Listed in: Science

Learning a force field from small-molecule crystal lattice predictions enables consistent sub-Angstrom protein-ligand docking

Published: Sept. 7, 2020, 9:01 p.m.
Duration: N/A

Listed in: Science

Transmission of allosteric response within the homotrimer of SARS-CoV-2 spike upon recognition of ACE2 receptor by the receptor-binding domain

Published: Sept. 7, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

Single-molecule FRET monitors CLC transporter conformation and subunit independence

Published: Sept. 7, 2020, 8:01 a.m.
Duration: N/A

Listed in: Science

The structural basis of the oncogenic mutant K-Ras4B homodimers

Published: Sept. 7, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Direct observation of RAG recombinase recruitment to chromatin and the IgH locus in live pro-B cells

Published: Sept. 7, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Determination of the molecular reach of the protein tyrosine phosphatase SHP-1

Published: Sept. 5, 2020, 6:03 a.m.
Duration: N/A

Listed in: Science

A myosin II-based nanomachine devised for the study of Ca2+-dependent mechanisms of muscle regulation

Published: Sept. 5, 2020, 6:03 a.m.
Duration: N/A

Listed in: Science

Dispatched conformational dynamics couples transmembrane Na+ flux to release of lipid-modified Hedgehog signal

Published: Sept. 5, 2020, 6:03 a.m.
Duration: N/A

Listed in: Science

In situ structure determination using single particle cryo-electron microscopy images

Published: Sept. 4, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

Histone tails cooperate to control the breathing of genomic nucleosomes

Published: Sept. 4, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Surface-catalyzed SAS-6 self-assembly directs centriole formation through kinetic and structural mechanisms

Published: Sept. 4, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Myosin-gelsolin cooperativity in actin filament severing and actomyosin motor activity

Published: Sept. 3, 2020, 3:04 p.m.
Duration: N/A

Listed in: Science

Inflammation mediates lung cancer-induced increase in the epidermal green autofluorescence of mice

Published: Sept. 3, 2020, 9:02 a.m.
Duration: N/A

Listed in: Science

Structural characterization of LsrK to target quorum sensing and comparison between X-ray and homology model

Published: Sept. 3, 2020, 8:02 a.m.
Duration: N/A

Listed in: Science

HPM Live μ for full CLEM workflow

Published: Sept. 3, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

qFit 3: Protein and ligand multiconformer modeling for X-ray crystallographic and single-particle cryo-EM density maps

Published: Sept. 3, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Pathogenic Mutations in the Kinesin-3 Motor KIF1A Diminish Force Generation and Movement Through Allosteric Mechanisms

Published: Sept. 3, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Principles of organelle membranebridging established using cytosolictether mimics

Published: Sept. 2, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

Intracellular stiffening competes with cortical softening in glioblastoma cells

Published: Sept. 2, 2020, 10:01 p.m.
Duration: N/A

Listed in: Science

A balance between matrix deformation and the coordination of turning events governs directed neutrophil migration in 3-D matrices

Published: Sept. 2, 2020, 10:01 p.m.
Duration: N/A

Listed in: Science

Insulin-Induced Conformational Changes in the Full-Length Insulin Receptor: Structural Insights Gained from Molecular Modeling Analyses

Published: Sept. 2, 2020, 10:02 a.m.
Duration: N/A

Listed in: Science

Self-similar action potential cycle-to-cycle variability of Ca2+ and current oscillators in cardiac pacemaker cells

Published: Sept. 2, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

Published: Sept. 2, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Molecular underpinnings of ssDNA specificity by Rep HUH endonucleases and implications for HUH-tag multiplexing and engineering

Published: Sept. 1, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Light dependent morphological changes can tune light absorption in iridescent plant chloroplasts

Published: Sept. 1, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Combination of photoactivation with lattice light-sheet imaging allows visualizing complex dorsal ruffling dynamics

Published: Sept. 1, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

The C-terminal actin binding domain of talin forms an asymmetric catch bond with F-actin

Published: Sept. 1, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Biological Noise in an Organelle Size Control System

Published: Sept. 1, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Water Controls Membrane Protein Stability

Published: Sept. 1, 2020, 4:02 a.m.
Duration: N/A

Listed in: Science

Confinement size determines the architecture of Ran-induced microtubule networks

Published: Sept. 1, 2020, 2:03 a.m.
Duration: N/A

Listed in: Science

Extreme stiffness of neuronal synapses and implications for synaptic adhesion and plasticity

Published: Sept. 1, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Tissue pressure and cell traction compensate to drive robust aggregate spreading

Published: Aug. 31, 2020, 7:02 p.m.
Duration: N/A

Listed in: Science

Size Effect on Structure and Stiffness of Viral DNA during Temperature Variation

Published: Aug. 31, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

To close or to collapse: the role of charges on membrane stability upon pore formation

Published: Aug. 31, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Exploring the evolutionary history of kinetic stability in the alpha-lytic protease family

Published: Aug. 31, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Quantitative characterization of the eukaryotic transcription cycle using live imaging and statistical inference

Published: Aug. 31, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Drug binding sites in the multidrug transporter MdfA in detergent solution and in lipid nanodiscs

Published: Aug. 31, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Micro-topographical guidance of macropinocytic signaling patches

Published: Aug. 31, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Imaging transmembrane dynamics of biomolecules at live cell plasma membranes using quenchers in extracellular environment

Published: Aug. 31, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Sequence-encoded and Composition-dependent Protein-RNA Interactions Control Multiphasic Condensate Topologies

Published: Aug. 31, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Nuclear stiffness decreases with disruption of the extracellular matrix in living tissues

Published: Aug. 31, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Student-focused development of a next-generation centrifuge force microscope

Published: Aug. 31, 2020, 12:03 a.m.
Duration: N/A

Listed in: Science

Confinement Discerns Swarmers from Planktonic Bacteria

Published: Aug. 30, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Predicting the tension in actin cytoskeleton from the nucleus shape

Published: Aug. 29, 2020, 6:02 a.m.
Duration: N/A

Listed in: Science

Non-Refoldability is Pervasive Across the E. coli Proteome

Published: Aug. 29, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

A Continuous Time Representation of smFRET for the Extraction of Rapid Kinetics

Published: Aug. 29, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Age and gender dependence of liver diffusion parameters and the evidence of intravoxel incoherent motion modelling of perfusion component is constrained by diffusion component.

Published: Aug. 29, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Lipoprotein particles interact with membranes and transfer their cargo without receptors

Published: Aug. 28, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

Cryo-EM structure of the MgtE Mg2+ channel pore domain in Mg2+-free conditions reveals cytoplasmic pore opening

Published: Aug. 28, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

Peptide-based Inhibitors of Protein-Protein Interactions of Src Homology 2 Domain-Containing Phosphatase 2

Published: Aug. 28, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Thermodynamic and mechanistic insights into coupled binding and unwinding of collagen by matrix metalloproteinase 1

Published: Aug. 28, 2020, 8:02 a.m.
Duration: N/A

Listed in: Science

Capturing non-local through-bond effects when fragmenting molecules for quantum chemical torsion scans

Published: Aug. 28, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

A Bitopic Miniprotein Regulates a Membrane-Embedded Enzyme via Topological Allostery

Published: Aug. 28, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

FRETboard: semi-supervised classification of FRET traces

Published: Aug. 28, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Ion-water coupling controls class A GPCR signal transduction pathways

Published: Aug. 28, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Structural characterization of Myxococcus xanthus MglC, a component of polarity control system, and its interactions with MglB

Published: Aug. 28, 2020, 3:01 a.m.
Duration: N/A

Listed in: Science

Glassiness in cellular Potts model of biological tissue is controlled by disordered energy landscape

Published: Aug. 28, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

Growth-laws and invariants from ribosome biogenesis in lower Eukarya

Published: Aug. 27, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Synergy of calcium release site determinants in control of calcium release events in cardiac myocytes

Published: Aug. 27, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Predicting Chemical Shifts with Graph Neural Networks

Published: Aug. 27, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

3D Deconvolution Processing for STEM Cryo-Tomography

Published: Aug. 27, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Mechanistic Studies of the Stabilization of Insulin Helical Structure by Coomassie Brilliant Blue

Published: Aug. 27, 2020, 11:01 a.m.
Duration: N/A

Listed in: Science

Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion

Published: Aug. 27, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Swirling Instability of the Microtubule Cytoskeleton

Published: Aug. 27, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Photobleaching step analysis for robust determination of protein complex stoichiometries

Published: Aug. 26, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

MMGBSA Consensus Estimate of the Binding Free Energy Between the Novel Coronavirus Spike Protein to the Human ACE2 Receptor

Published: Aug. 26, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Use of High Pressure NMR Spectroscopy to Rapidly Identify Proteins with Internal Ligand-Binding Voids

Published: Aug. 26, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

A physical theory of larval Drosophila behaviour

Published: Aug. 25, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

Could radical pairs play a role in xenon-induced general anesthesia?

Published: Aug. 25, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Confocal Laser-Scanning Fluorescence-Lifetime Single-Molecule Localisation Microscopy

Published: Aug. 25, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Decoding the physical principles of two-component biomolecular phase separation

Published: Aug. 24, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

Dataset of the construction and characterization of stable biological nanoparticles

Published: Aug. 24, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

Disinfection chemicals mode of action on the bacterial spore structure and their Raman spectra

Published: Aug. 24, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

N-terminus of the third PDZ Domain of PSD-95 Orchestrates Allosteric Communication for Selective Ligand Binding

Published: Aug. 24, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Light-emitting diode-based transcranial photoacoustic measurement of sagittal sinus oxyhemoglobin saturation in hypoxic neonatal piglets

Published: Aug. 24, 2020, 6:04 p.m.
Duration: N/A

Listed in: Science

Self-generated persistent random forces drive phase separation in growing tumors

Published: Aug. 24, 2020, 6:03 p.m.
Duration: N/A

Listed in: Science

Theoretical basis for stabilizing messenger RNA through secondary structure design

Published: Aug. 24, 2020, 6:03 p.m.
Duration: N/A

Listed in: Science

Deciphering the mechanical code of genome and epigenome

Published: Aug. 24, 2020, 6:03 p.m.
Duration: N/A

Listed in: Science

Auxetic Two-Dimensional Nanostructures from DNA

Published: Aug. 24, 2020, 5:01 p.m.
Duration: N/A

Listed in: Science

Fast Ion Beam Inactivation of Viruses, Where Radiation Track Structure Meets RNA Structural Biology.

Published: Aug. 24, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Mechanism and kinetics of copper complexes binding to the influenza A M2 channel

Published: Aug. 24, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Dynamics of the N-terminal domain of SARS-CoV-2 nucleocapsid protein drives dsRNA melting in a counterintuitive tweezer-like mechanism

Published: Aug. 24, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Double-transmembrane domain reduces fusion rate by increasing lipid-protein mismatch

Published: Aug. 24, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Statistics and classification of spatial rotations and projection directions considering molecular symmetry in 3D electron cryo-microscopy

Published: Aug. 24, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Emerging Tumor Development by Simulating Single-cell Events

Published: Aug. 24, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Base pairing and stacking contributions to double stranded DNA formation

Published: Aug. 23, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Phosphate binding induced force-reversal occurs via slow backward cycling of cross-bridges

Published: Aug. 23, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Mechanical Activation of MscL Revealed by a Locally Distributed Tension Molecular Dynamics Approach

Published: Aug. 23, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Dynamic nuclear structure emerges from chromatin crosslinks and motors

Published: Aug. 23, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

The N34S mutation of SPINK1 may impact the kinetics of trypsinogen activation to cause early trypsin release in the pancreas

Published: Aug. 23, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Emap2sec+: Detecting Protein and DNARNA Structures in Cryo-EM Maps of Intermediate Resolution Using Deep Learning

Published: Aug. 23, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Contributions by N-terminal Domains to NMDA Receptor Currents

Published: Aug. 23, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Serial femtosecond and serial synchrotron crystallography yield data of equivalent quality: a systematic comparison

Published: Aug. 22, 2020, 7:03 a.m.
Duration: N/A

Listed in: Science

Activation of G-protein coupled receptors is thermodynamically linked to lipid solvation

Published: Aug. 21, 2020, 5:01 p.m.
Duration: N/A

Listed in: Science

Inoculum effect of antimicrobial peptides

Published: Aug. 21, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Routine sub-2.5 A cryo-EM structure determination of B-family G protein-coupled receptors

Published: Aug. 21, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Dynamics of mechanically coupled hair-cell bundles of the inner ear

Published: Aug. 21, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Histidine Protonation Controls Structural Heterogeneity in the Cyanobacteriochrome AnPixJg2

Published: Aug. 21, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation

Published: Aug. 21, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding

Published: Aug. 20, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

Photocatalytic plant LPOR forms helical lattices that shape membranes for chlorophyll synthesis

Published: Aug. 20, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

The Response of Bacterial Flagellar Motor to Stepwise Increase in NaCl Concentration

Published: Aug. 20, 2020, 7:01 p.m.
Duration: N/A

Listed in: Science

Conformational ordering of intrinsically disordered peptides for targeting translation initiation

Published: Aug. 20, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Latent dynamical variables produce signatures of spatiotemporal criticality in large biological systems

Published: Aug. 20, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Agonist and antagonist diverted twisting motions of single TRPV1 channel

Published: Aug. 19, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Mechanism of negative membrane curvature generation by the IRSP53 I-BAR domain

Published: Aug. 19, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Epigenetic memory as a time integral over prior history of Polycomb phase separation

Published: Aug. 19, 2020, 6:01 p.m.
Duration: N/A

Listed in: Science

Resolving Individual-Atom of Protein Complex using Commonly Available 300-kV Cryo-electron Microscopes

Published: Aug. 19, 2020, 5:01 p.m.
Duration: N/A

Listed in: Science

Autocorrelation-based method to identify disordered rhythm in Parkinsons disease tasks: a novel approach applicable to multimodal devices

Published: Aug. 19, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Probing the Hidden Sensitivity of Intrinsically Disordered Proteins to their Chemical Environment

Published: Aug. 18, 2020, 8:02 p.m.
Duration: N/A

Listed in: Science

A Molecular View of Lipid-mediated Activation Process of Apolipoprotein E

Published: Aug. 18, 2020, 4:02 p.m.
Duration: N/A

Listed in: Science

Ligation of random oligomers leads to emergence of autocatalytic sequence network

Published: Aug. 18, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

Measuring DNA mechanics on the genome scale

Published: Aug. 18, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

Probing acetylated-α-synuclein monomer-aggregate complexes by NMR elucidates mechanism of fibril seeding

Published: Aug. 18, 2020, 3:02 p.m.
Duration: N/A

Listed in: Science

Fitting side-chain NMR relaxation data using molecular simulations

Published: Aug. 18, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Assessment of Structural Units Deletions in the Archaeal Oligosaccharyltransferase AglB

Published: Aug. 18, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

Published: Aug. 18, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

A workflow for sizing oligomeric biomolecules based on cryo single molecule localization microscopy

Published: Aug. 17, 2020, 8:01 a.m.
Duration: N/A

Listed in: Science

Cellular pathways of calcium transport and concentration towards mineral formation in sea urchin larvae

Published: Aug. 17, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Sticking around: Optimal cell adhesion patterning for energy minimization and substrate mechanosensing

Published: Aug. 17, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment

Published: Aug. 16, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

How mu-Opioid Receptor Recognizes Fentanyl

Published: Aug. 16, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

C3' Stereocentre of Furanose Determines the Helicity of Double-Stranded Nucleic Acids: Towards Etiology of Nucleic Acids

Published: Aug. 16, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Enhancing SNR and generating contrast for cryo-EM images with convolutional neural networks

Published: Aug. 16, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Fibroblasts close a void in free space by a purse-string mechanism

Published: Aug. 15, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Ligand Effects on Phase Separation of Multivalent Macromolecules

Published: Aug. 15, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

Wavelet coherence phases decode the universal switching mechanism of Ras GTPase superfamily

Published: Aug. 15, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Probing nanoscale diffusional heterogeneities in cellular membranes through multidimensional single-molecule and super-resolution microscopy

Published: Aug. 15, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

The Automated Optimisation of a Coarse-Grained Force Field Using Free Energy Data

Published: Aug. 14, 2020, 11:02 p.m.
Duration: N/A

Listed in: Science

A benchmarking model for validation and standardization of traction force microscopy analysis tools

Published: Aug. 14, 2020, 11:02 p.m.
Duration: N/A

Listed in: Science

Extraction of accurate cytoskeletal actin velocity distributions from noisy measurements

Published: Aug. 14, 2020, 10:01 p.m.
Duration: N/A

Listed in: Science

A power amplification dyad in seahorses

Published: Aug. 14, 2020, 10:01 p.m.
Duration: N/A

Listed in: Science

Ca2+ release via IP3Rs increases RyR mediated Ca2+ spark frequency in ventricular cardiomyocytes without altering spark amplitude and duration

Published: Aug. 14, 2020, 10:01 a.m.
Duration: N/A

Listed in: Science

Single-molecule view of coordination in a multi-functional DNA polymerase

Published: Aug. 14, 2020, 10:01 a.m.
Duration: N/A

Listed in: Science

Low-cost, bottom-up fabrication of large-scale single-molecule nanoarrays by DNA origami placement

Published: Aug. 14, 2020, 2:01 a.m.
Duration: N/A

Listed in: Science

Molecular crowding in single eukaryotic cells: using cell environment biosensing and single-molecule optical microscopy to probe dependence on ionic strength, glucose conditions, and copy number

Published: Aug. 14, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

The Protein Hourglass: Exact First Passage Time Distributions for Protein Thresholds

Published: Aug. 14, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Influenza A virus diffusion through mucus gel networks

Published: Aug. 14, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Long-lasting salt bridges provide the anchoring mechanism of oncogenic KRas-4B at cell membranes

Published: Aug. 14, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

Cell-Scale Biophysical Cues from Collagen Fiber Architecture Instruct Cell Behavior and the Propagation of Mechanosensory Signals

Published: Aug. 13, 2020, 10:02 a.m.
Duration: N/A

Listed in: Science

Correlative single-molecule fluorescence barcoding of gene regulation in Saccharomyces cerevisiae

Published: Aug. 13, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Kinetic analysis reveals the rates and mechanisms of protein aggregation in a multicellular organism

Published: Aug. 13, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Short-wavelength-sensitive 2 (Sws2) visual photopigment models combined with atomistic molecular simulations to predict spectral peaks of absorbance

Published: Aug. 13, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Highly-parallel, microfluidics-based force spectroscopy on single motor proteins

Published: Aug. 12, 2020, 11:01 p.m.
Duration: N/A

Listed in: Science

Structural basis for transcription complex disruption by the Mfd translocase

Published: Aug. 12, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Multiscale simulations examining glycan shield effects on drug binding to influenza neuraminidase

Published: Aug. 12, 2020, 4:01 a.m.
Duration: N/A

Listed in: Science

Multimodal Label-free Monitoring of Adipogenic Stem Cell Differentiation using Endogenous Optical Biomarkers

Published: Aug. 12, 2020, 2:05 a.m.
Duration: N/A

Listed in: Science

Diffusive dynamics of Aspartate α-decarboxylase (ADC) liganded with D-serine in aqueous solution

Published: Aug. 12, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

In situ measurement of the isoplanatic patch for imaging through intact bone

Published: Aug. 11, 2020, 2:02 p.m.
Duration: N/A

Listed in: Science

Swarming bacteria undergo localized dynamic phase transition to form stress-induced biofilms

Published: Aug. 11, 2020, 2:02 p.m.
Duration: N/A

Listed in: Science

A 3.4-A cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles

Published: Aug. 11, 2020, 2:02 p.m.
Duration: N/A

Listed in: Science

Proteome-scale Analysis of Vertebrate Protein Thermoadaptation Modulated by Dynamic Allostery And Protein Solvation

Published: Aug. 11, 2020, 2:02 p.m.
Duration: N/A

Listed in: Science

Resolving the data asynchronicity in high-speed atomic force microscopy measurement via the Kalman Smoother

Published: Aug. 11, 2020, 2:02 p.m.
Duration: N/A

Listed in: Science

Chemotactic Migration of Bacteria in Porous Media

Published: Aug. 11, 2020, 2:02 p.m.
Duration: N/A

Listed in: Science

Ebselen Reacts with SARS Coronavirus-2 Main Protease Crystals

Published: Aug. 10, 2020, 1:02 p.m.
Duration: N/A

Listed in: Science

TRPV2 interaction with small molecules and lipids revealed by cryo-EM

Published: Aug. 10, 2020, 1:02 p.m.
Duration: N/A

Listed in: Science

DEER-PREdict: Software for Efficient Calculation of Spin-Labeling EPR and NMR Data from Conformational Ensembles

Published: Aug. 10, 2020, 1:02 p.m.
Duration: N/A

Listed in: Science

Two modes of PRC1-mediated mechanical resistance to kinesin-driven microtubule network disruption

Published: Aug. 10, 2020, 1:02 p.m.
Duration: N/A

Listed in: Science

Computational Tool for Ensemble Averaging of Single-Molecule Data

Published: Aug. 10, 2020, 1:01 p.m.
Duration: N/A

Listed in: Science

Membrane composition and lipid to protein ratio modulate amyloid kinetics of yeast prion protein

Published: Aug. 7, 2020, 12:04 a.m.
Duration: N/A

Listed in: Science

Single-molecule studies of conformational states and dynamics in the ABC importer OpuA

Published: Aug. 7, 2020, 12:04 a.m.
Duration: N/A

Listed in: Science

Theory of genetic oscillations with external noisy regulation

Published: Aug. 7, 2020, 12:04 a.m.
Duration: N/A

Listed in: Science

Multivalent interactions between eIF4G1, Pub1 and Pab1 drive the formation of protein condensates

Published: Aug. 7, 2020, 12:04 a.m.
Duration: N/A

Listed in: Science

Ribosome fingerprinting with a solid-state nanopore

Published: Aug. 7, 2020, 12:03 a.m.
Duration: N/A

Listed in: Science

Liquid-liquid phase separation of tau driven by hydrophobic interaction facilitates fibrillization of tau

Published: Aug. 6, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

PI3K inhibition reverses migratory direction of single cells but not cell groups in electric field

Published: Aug. 6, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

Molecular details of protein condensates probed by microsecond-long atomistic simulations

Published: Aug. 6, 2020, 4:01 p.m.
Duration: N/A

Listed in: Science

CorRelator: An interactive and flexible toolkit for high-precision cryo-correlative light and electron microscopy

Published: Aug. 6, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Ripples at edges of blooming lilies and torn plastic sheets

Published: Aug. 6, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

The emergence of phase separation as an organizing principle in bacteria

Published: Aug. 6, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Thermodynamics of DNA Hybridization from Atomistic Simulations

Published: Aug. 6, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Continuous Constant pH Molecular Dynamics of Transmembrane Proteins

Published: Aug. 6, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody

Published: Aug. 6, 2020, 5:02 a.m.
Duration: N/A

Listed in: Science

Signatures and mechanisms of efficacious therapeutic ribonucleotides against SARS-CoV-2 revealed by analysis of its replicase using magnetic tweezers

Published: Aug. 6, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Investigating the effects of molecular crowding on the kinetics of protein aggregation

Published: Aug. 6, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Computational Hot-Spot Analysis of the SARS-CoV-2 Receptor Binding Domain ACE2 Complex

Published: Aug. 6, 2020, 1:02 a.m.
Duration: N/A

Listed in: Science

High-precision protein-tracking with interferometric scattering microscopy

Published: Aug. 4, 2020, 7:05 p.m.
Duration: N/A

Listed in: Science

Muscle activity of cutting manoeuvres and soccer inside passing suggests an increased groin injury risk during these movements

Published: Aug. 4, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Circumventing the optical diffraction limit with customized speckles

Published: Aug. 3, 2020, 9:01 p.m.
Duration: N/A

Listed in: Science

Mechanism of duplex unwinding by coronavirus nsp13 helicases

Published: Aug. 3, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Glycine Rich Segments Adopt Polyproline II Helices Which May Contribute to Biomolecular Condensate Formation

Published: July 31, 2020, 8:01 p.m.
Duration: N/A

Listed in: Science

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation

Published: July 31, 2020, 4:01 a.m.
Duration: N/A

Listed in: Science

Biomechanical Characterization of SARS-CoV-2 Spike RBD and Human ACE2 Protein-Protein Interaction

Published: July 31, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

High speed, three-dimensional imaging reveals chemotactic behavior specific to human-infective Leishmania parasites

Published: July 31, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Computer Simulations of the interaction between SARS-CoV-2 spike glycoprotein and different surfaces

Published: July 31, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Comparative study of curvature sensing mediated by F-BAR domain and an intrinsically disordered region of FBP17

Published: July 31, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase

Published: July 31, 2020, 1:01 a.m.
Duration: N/A

Listed in: Science

Towards chemical accuracy for alchemical free energy calculations with hybrid physics-based machine learning molecular mechanics potentials

Published: July 30, 2020, 5:01 p.m.
Duration: N/A

Listed in: Science

Unfolding of the chromatin fiber driven by overexpression of bridging factors

Published: July 30, 2020, 3:01 p.m.
Duration: N/A

Listed in: Science

Single-Molecule Micromanipulation Studies Of Methylated DNA

Published: July 30, 2020, 10:02 a.m.
Duration: N/A

Listed in: Science

Control and mechanisms of pulsatile flows in epithelial monolayers

Published: July 30, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

High-Pressure NMR Reveals Volume and Compressibility Differences Between Two Stably Folded Protein Conformations

Published: July 30, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Viscoelastic properties of wheat gluten in a molecular dynamics study

Published: July 30, 2020, 9:01 a.m.
Duration: N/A

Listed in: Science

Disease-Linked Super-Trafficking of a Mutant Potassium Channel

Published: July 29, 2020, 8:01 a.m.
Duration: N/A

Listed in: Science

Radiation-induced cell cycle perturbations: acomputational tool validated with flow-cytometrydata

Published: July 29, 2020, 7:02 a.m.
Duration: N/A

Listed in: Science

Allosteric inhibition of the SARS-CoV-2 main protease - insights from mass spectrometry-based assays

Published: July 29, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

On the molecular mechanism of SARS-CoV-2 retention in the upper respiratory tract

Published: July 29, 2020, 5:01 a.m.
Duration: N/A

Listed in: Science

Crystal structure reveals the full Ras:Raf interface and advances mechanistic understanding of Raf activation

Published: July 29, 2020, 3:01 a.m.
Duration: N/A

Listed in: Science

Cell-to-cell Mathematical Modeling of Arrhythmia Phenomena in the Heart

Published: July 29, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Long-range coupled motions underlie ligand recognition by a chemokine receptor

Published: July 29, 2020, 2:02 a.m.
Duration: N/A

Listed in: Science

Generalizing HMMs to Continuous Time for Fast Kinetics: Hidden Markov Jump Processes

Published: July 29, 2020, 1:04 a.m.
Duration: N/A

Listed in: Science

UNCG RNA tetraloop as a formidable force-field challenge for MD simulations

Published: July 29, 2020, 1:03 a.m.
Duration: N/A

Listed in: Science

Thermodynamics and kinetics of the amyloid-β peptide revealed by Markov state models based on MD data in agreement with experiment

Published: July 29, 2020, 1:03 a.m.
Duration: N/A

Listed in: Science

Dynamic signatures of lipid droplets as new markers to quantify cellular metabolic changes

Published: July 29, 2020, 1:03 a.m.
Duration: N/A

Listed in: Science

Mind reading of the proteins: Deep-learning to forecast molecular dynamics

Published: July 29, 2020, 1:03 a.m.
Duration: N/A

Listed in: Science

Residence Time Analysis of RNA Polymerase Transcription Dynamics: A Bayesian Sticky HMM Approach

Published: July 29, 2020, 12:01 a.m.
Duration: N/A

Listed in: Science

Multicolor structured illumination microscopy and quantitative control of coherent light with a digital mirror device

Published: July 28, 2020, 10:52 p.m.
Duration: N/A

Listed in: Science

Influence of membrane-cortex linkers on the extrusion of membrane tubes

Published: July 28, 2020, 10:46 p.m.
Duration: N/A

Listed in: Science

Three-Dimensional Label-Free Imaging and Quantification of Migrating Cells during Wound Healing

Published: July 28, 2020, 5:17 p.m.
Duration: N/A

Listed in: Science

Nucleation-dependent aggregation kinetics of Yeast Sup35 fragment GNNQQNY

Published: July 28, 2020, 7:01 a.m.
Duration: N/A

Listed in: Science

Temperature Dependence of the Krokinobacter rhodopsin 2 Kinetics

Published: July 27, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Weak catch bonds make strong networks

Published: July 27, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Connecting the stimuli-responsive rheology of biopolymer hydrogels to underlying hydrogen-bonding interactions

Published: July 27, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L

Published: July 27, 2020, 6:01 a.m.
Duration: N/A

Listed in: Science

SMAP - A Modular Superresolution Microscopy Analysis Platform for SMLM Data

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Inhibitory and Transport Mechanisms of the Human Cation-Chloride Cotransport KCC1

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

The metal cofactor zinc and interacting membranes modulate SOD1 conformation-aggregation landscape in an in vitro ALS Model

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Megadalton-sized dityrosine aggregates of α-synuclein retain high degrees of structural disorder and internal dynamics.

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Structure of voltage-modulated sodium-selective NALCN-FAM155A channel complex

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Unifying framework for the diffusion of microscopic particles in mucus

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Are Granulins Copper Sequestering Proteins?

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

The SARS-CoV-2 Spike Variant D614G Favors an Open Conformational State

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Extensions of the worm-like-chain model to tethered active filaments under tension

Published: July 26, 2020, 7:31 p.m.
Duration: N/A

Listed in: Science

Structure of human sodium leak channel NALCN in complex with FAM155A

Published: July 25, 2020, 9:08 p.m.
Duration: N/A

Listed in: Science

Biophysical and dynamic characterization of a fine-tuned binding of the human Respiratory Syncytial Virus M2-1 core domain to long RNAs

Published: July 25, 2020, 9:08 p.m.
Duration: N/A

Listed in: Science

Effect of cholesterol vs. ergosterol on DPPC bilayer properties: insights from atomistic simulations

Published: July 25, 2020, 9:08 p.m.
Duration: N/A

Listed in: Science

Data-guided Multi-Map variables for ensemble refinement of molecular movies

Published: July 24, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Protein sequence design by explicit energy landscape optimization

Published: July 24, 2020, 9:08 p.m.
Duration: N/A

Listed in: Science

Elucidation of cryptic and allosteric pockets within the SARS-CoV-2 protease

Published: July 24, 2020, 9:08 p.m.
Duration: N/A

Listed in: Science

Coupling between lipid miscibility and phosphotyrosine driven protein condensation at the membrane

Published: July 23, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Activation microswitches in GPCRs function as rheostats in cell membrane

Published: July 23, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Multiple-labeled antibodies behave like single emitters in photoswitching buffer

Published: July 23, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Local structure of DNA toroids reveals curvature-dependent intermolecular forces

Published: July 23, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Direct Photon-by-photon Analysis of Time-Resolved Pulsed Excitation Data using Bayesian Nonparametrics

Published: July 22, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

In Situ Unzipping of Long, High Molecular Weight DNA in Solid State Nanopores

Published: July 22, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Specific interaction of Penetratin with cell surface partners measured with biomembrane force probe

Published: July 22, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Electric field mediated fibronectin hydroxyapatite interaction: A molecular insight

Published: July 22, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Light-powered reactivation of flagella: towards self-sustained movement of artificial cells

Published: July 21, 2020, 9:10 p.m.
Duration: N/A

Listed in: Science

Three-dimensional beating dynamics of Chlamydomonas flagella

Published: July 21, 2020, 9:10 p.m.
Duration: N/A

Listed in: Science

Resistive force theory and wave dynamics in swimming isolated flagellar apparatus

Published: July 21, 2020, 9:10 p.m.
Duration: N/A

Listed in: Science

An integrative structural model of the full-length gp16 ATPase in bacteriophage phi29 DNA packaging motor

Published: July 21, 2020, 9:10 p.m.
Duration: N/A

Listed in: Science

Vesicle Navigation of Microtubule Ends Distinguished by A Single Rate-Constant Model

Published: July 21, 2020, 9:10 p.m.
Duration: N/A

Listed in: Science

3D-Visualization of Amyloid-β Oligomer and Fibril Interactions with Lipid Membranes by Cryo-Electron Tomography

Published: July 21, 2020, 9:10 p.m.
Duration: N/A

Listed in: Science

Molecular mechanism of SARS-CoV-2 cell entry inhibition via TMPRSS2 by Camostat and Nafamostat mesylate

Published: July 21, 2020, 9:09 p.m.
Duration: N/A

Listed in: Science

Protein Structure Refinement Guided by Atomic Packing Frustration Analysis

Published: July 20, 2020, 9:10 p.m.
Duration: N/A

Listed in: Science

Computational optimization of the SARS-CoV-2 receptor-binding-motif affinity for human ACE2

Published: July 20, 2020, 9:10 p.m.
Duration: N/A

Listed in: Science

Quantitative mapping of membrane nanoenvironments through single-molecule imaging of solvatochromic probes

Published: July 19, 2020, 9:11 p.m.
Duration: N/A

Listed in: Science

Theoretical analysis predicts an optimal therapeutic strategy in distinct parkinsonian landscapes of the striatum

Published: July 19, 2020, 9:11 p.m.
Duration: N/A

Listed in: Science

Effect of shear and tensile loading on fibrin molecular structure revealed by coherent Raman microscopy

Published: July 19, 2020, 9:11 p.m.
Duration: N/A

Listed in: Science

The KDEL Trafficking Receptor Exploits pH to Tune the Strength of an Unusual Short Hydrogen Bond.

Published: July 18, 2020, 9:11 p.m.
Duration: N/A

Listed in: Science

A series of Orai1 gating checkpoints in transmembrane and cytosolic regions requires clearance for CRAC channel opening Clearance and synergy of Orai1 gating checkpoints controls pore opening

Published: July 17, 2020, 9:11 p.m.
Duration: N/A

Listed in: Science

Experimental study of microbial induced carbonate precipitation (MICP) in the presence of CaCO3 seeds

Published: July 17, 2020, 9:11 p.m.
Duration: N/A

Listed in: Science

Actin bundle architecture and mechanics regulate myosin II force generation

Published: July 17, 2020, 9:11 p.m.
Duration: N/A

Listed in: Science