TWiV 995: Viral origin stories

Published: March 26, 2023, 4 a.m.

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TWiV discusses genetic evidence of susceptible wildlife in SARS-CoV-2 positive samples at the Huanan Wholesale Seafood Market, polio cases in African linked to a new polio vaccine that was designed to not cause the disease, and structural conservation of hepatitis B virus capsid proteins over millions of years despite a shift from a naked to an enveloped capsid.

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Download TWiV 995 (74 MB .mp3, 123 min)
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\\u2022MicrobeTV Discord Server
\\u2022 More evidence for SARS-CoV-2 spillover (Zenodo)
\\u2022Polio cases linked to nOPV2 (Science; GPEI statement)
\\u2022nOPV2 on TWiV 756
\\u2022Engineering OPV to prevent reversion to neurovirulence (Cell Host Microbe)
\\u2022Stability of nOPV2 in children (npj Vaccines)
\\u20222A changes compensate for 5\\u2032-UTR disruptions (Virology)
\\u2022HBV shifts from naked to enveloped (Nat Comm)
\\u2022Letters read\\xa0on TWiV 995
\\u2022Timestamps by\\xa0Jolene. Thanks!

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