TWiV 984: Clinical update with Dr. Daniel Griffin
b'
In his weekly clinical update Dr. Griffin discusses the political polarization of COVID-19 treatments among physicians and laypeople in the United States, seven alternatives to evidence-based medicine, Malawi\\u2019s cholera death toll crosses 1,300 in its deadliest outbreak on record, impact of coronavirus infections on pediatric patients at a tertiary pediatric hospital, maternal mRNA COVID-19 vaccination during pregnancy and delta or omicron infection or hospital admission in infants, yes masks reduce the risk of spreading infection, despite a review saying they don\\u2019t, COVID-19 and airborne transmission: science rejected, lives lost. can society do better, what were the historical reasons for the resistance to recognizing airborne transmission during the COVID-19 pandemic, a randomized trial comparing Omicron-containing boosters with the original COVID-19 vaccine mRNA-1273, SARS-CoV-2 neutralizing antibodies after bivalent vs. monovalent booster, the impacts of SARS-CoV-2 vaccine dose separation and targeting on the COVID-19 epidemic in England, intra-host evolution provides for the continuous emergence of SARS-CoV-2 variants, real-world use of Nirmatrelvir\\u2013Ritonavir in outpatients with COVID-19 during the era of Omicron variants including BA.4 and BA.5 in Colorado, viral burden rebound in hospitalized patients with COVID-19 receiving oral antivirals in Hong Kong, and guidance on the use of convalescent plasma to treat immunocompromised patients with COVID-19.
Subscribe (free): Apple Podcasts,\\xa0Google Podcasts,\\xa0RSS,\\xa0email
Become a\\xa0patron\\xa0of\\xa0TWiV!
Links for this episode
- The\\xa0political polarization\\xa0of COVID-19 treatments in the United States (PNAS)
- Seven alternatives to\\xa0evidence-based medicine\\xa0(BMJ)
- Malawi\\u2019s\\xa0cholera death toll\\xa0crosses 1,300 (CBC)
- Impact\\xa0of coronavirus infections on pediatric patients (JHI)
- Maternal mRNA\\xa0COVID-19 vaccination\\xa0during pregnancy (BMJ)
- Yes, masks reduce the\\xa0risk of spreading COVID\\xa0(TVO)
- COVID-19\\xa0and airborne transmission (IDSA)
- What were the reasons for\\xa0resistance\\xa0to recognizing airborne transmission (IJIE)
- Comparing\\xa0Omicron-containing boosters with COVID-19 vaccine mRNA-1273 (medRxiv)
- SARS-CoV-2\\xa0neutralizing antibodies\\xa0after bivalent vs. monovalent booster (bioRxiv)
- The impact of SARS-CoV-2 vaccine\\xa0dose separation and targeting\\xa0(Nature)
- Intra-host evolution\\xa0provides for the emergence of SARS-CoV-2 variants (ASM)
- Real-world use of\\xa0nirmatrelvir\\u2013ritonavir\\xa0in outpatients with COVID-19 (The Lancet)
- Viral rebound in hospitalized patients with COVID-19\\xa0receiving oral antivirals\\xa0(The Lancet)
- Guidance on the\\xa0use of convalescent plasma\\xa0to treat immunocompromised patients with COVID-19 (CID)
- Contribute to our\\xa0ASTMH fundraiser at PWB
- Dr. Griffin\\u2019s treatment guide (pdf)
- Letters read\\xa0on TWiV 984
- Don\\u2019t crush Paxlovid (pdf)
- Timestamps by\\xa0Jolene. Thanks!
Intro music is by\\xa0Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv