TWiV 932: Clinical update with Dr. Daniel Griffin
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In his weekly clinical update Dr. Griffin discusses vaccine effectiveness against influenza illness in children,\\xa0clinical manifestations of infection with poliovirus, spike protein-independent attenuation of SARS-CoV-2 Omicron variant in laboratory mice, concordance of SARS-CoV-2 results in self-collected nasal swabs vs swabs collected by health care workers in children and adolescents,\\xa0probable animal-to-human transmission of\\xa0SARS-CoV-2\\xa0causing a pet shop-related outbreak,\\xa0laboratory-confirmed COVID-19\\u2013associated hospitalizations among adults during BA.2 variant, SARS-CoV-2 specific T-cells and antibodies,\\xa0Nirmatrelvir use and outcomes during the Omicron surge,\\xa0real-world effectiveness of early Molnupiravir or Nirmatrelvir\\u2013ritonavir in hospitalized patients, and\\xa0distinguishing features of long COVID.
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Links for this episode
- Vaccine effectiveness\\xa0against Influenza illness in children (CID)
- Clinical manifestations of infection with\\xa0Polio\\xa0(JAMA)
- Characteristics of deaths\\xa0among fully vaccinated persons with Coronavirus (CID)
- Spike protein attenuation of\\xa0Omicron Variant in lab mice\\xa0(Cell Reports)
- Concordance of\\xa0SARS-CoV-2 results\\xa0in nasal swabs self-collected vs healthcare collected (JAMA)
- Probable\\xa0animal-to-human transmission\\xa0of Sars-Cov-2 (CID)
- PAXLOVID patient eligibility\\xa0screening checklist (FDA)
- Remdesivir fact sheet\\xa0for providers (Veklury)\\xa0
- Bebtelovimab fact sheet\\xa0for providers (FDA)
- COVID-19\\u2013associated hospitalizations\\xa0among adults during BA.2 variant (CDC)
- Sars-Cov-2 specific\\xa0T-cells and antibodies\\xa0(CID)
- Nirmatrelvir use and outcomes\\xa0during the Omicron surge (NEJM)
- Effectiveness of\\xa0early\\xa0Molnupiravir or Nirmatrelvir\\u2013Ritonavir\\xa0in hospitalized patients (The Lancet)
- Distinguishing features of\\xa0long COVID\\xa0(medRxiv)
- Unexplained post-acute infection syndromes (Nature Med)
- Contribute to\\xa0Floating Doctors fundraiser at PWB
- Dr. Griffin\\u2019s treatment guide (pdf)
- Letters read\\xa0on TWiV 932
- Timestamps by Jolene. Thanks!
Intro music is by\\xa0Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv