TWiV 742: De-fusing COVID-19
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TWiV reviews a drug screen for inhibitors of syncytium formation, the fusing of cells caused by SARS-CoV-2, which reveals that the process is regulated by a calcium-activated ion channel and scramblase that is inhibited by the anti-parasite drug Niclosamide.
Hosts:\\xa0Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker
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Links for this episode
- TMEM16 inhibitors block SARS-CoV-2 driven syncytium formation (Nature)
- Letters read on TWiV 742
- Timestamps by Jolene. Thanks!
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