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The paratenic hosts reveal a case of scabies in the Traveling Salesman, and discuss a role for natural antibody in protection from infection with\\xa0Plasmodium.

Hosts:\\xa0Vincent Racaniello,\\xa0Dickson Despommier, and Daniel Griffin

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Links for this episode:

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• Parasite\\xa0Nobel Prizes 2015
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• Ivermectin\\xa0story (Nat Rev Micro)
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• Ivermectin\\xa0target\\xa0(Brain Res)
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• Gut microbiota and\\xa0Plasmodium\\xa0protection\\xa0(Cell)
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• Natural antibody\\xa0(virology blog)
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• Image credit
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• Letters read\\xa0on TWiP 97
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Case study for TWiP 97

Daniel has two cases this week.\\xa0Two people with similar presentations. A 12 yo girl in Peru presented for care with painless dark brown area on right knee. Has brothers and sisters, often play together. No trauma, but area is expanding. Months later develops cognitive changes. Second case is a\\xa05 yo boy from the coastal region of Peru brought in by Mother, has red swollen area on face. Mom says while playing scratched nose, swelling right cheek, eye, nasal obstruction, no response to antibiotics.\\xa0MRI of both show infiltrating process. Girl, left side of brain, middle cerebral artery territory. Boy in frontal region, midline area.\\xa0Thus both skin lesions associated with infiltrating process in brain. Came into clinic months after lesions started, and lesions still present.

Send your diagnosis to\\xa0twip@twiv.tv

Contact

Send your questions and comments (email or mp3 file) to\\xa0twip@twiv.tv

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