TWiP 218: Malaria parasite evades mosquito
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TWiP solves two cases this week, the Man with Issues after COVID-19, and the Man with Left Arm Weakness, then describe how the malaria parasite evades mosquito immunity by glutaminyl cyclase\\u2013mediated posttranslational protein modification.
Hosts:\\xa0Vincent Racaniello,\\xa0Daniel Griffin, and Christina Naula
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Links for this episode
- Malaria parasite evades\\xa0mosquito immunity\\xa0(Proc Natl Acad Sci USA)
- Letters read\\xa0on TWiP 218
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Case Study for TWiP 218
A fun twist for today. Did I mention recently I was spending time with Paul Calle at the Central Park and instead of Jeff Bezos showing up for Dinner Chevy Chase was there.
Here we have the case of a 19 month old female who seems to be having some issues. Lots of increased respiratory effort even with minimal exertion. Some issue with loose stools and then followed by the onset of facial swelling.\\xa0 No sig PMH or PSH, fairly confident there is not smoking or drinking of alcohol and certainly not HIV+. On exam the increased respiratory effort that is audible.
Directed testing reveals canine coccidia and giardia in the stool.
So what is going on? Should I be worried about my daughter who has had lots of exposure?
Send your case diagnosis, questions and comments to\\xa0twip@microbe.tv
Music by\\xa0Ronald Jenkees
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