TWiP 174: Fat cat
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Hosts:\\xa0Vincent Racaniello, Dickson Despommier, and\\xa0Daniel Griffin
The TWiPloid organisms solve the case of the Doctor with Chronic Epigastric Pain, and reveal how levels of linoleic acid in the intestine enable the sexual cycle of Toxoplasma gondii\\xa0in cats.
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Links for this episode:
- Determinant of T. gondii sexual cycle(bioRxiv)
- A Year\'s Worth of TWiP\\xa0by Kevin Carney
- Hero: William Trager
- Letters read\\xa0on TWiP 174
Become a\\xa0patron\\xa0of TWiP.
Case Study for TWiP 174
12 yo male living in refugee camp after fleeing Sudan. Presents to doctor with history of fever for many months, every other day; chronic abdominal pain. Tried antimalarials, no effect. Broad spectrum antibiotics, no effect. Exam: fast heart, clear lung, enlarged liver, enlarged palpable spleen. Camp has limited resources, no more diagnostic tests. Tried intravenous amphotericin. Child improves. \\xa0
Send your case diagnosis, questions and comments to\\xa0twip@microbe.tv
Music by\\xa0Ronald Jenkees
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