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ESUS, CAC 0, Takotsubo syndrome, and chest pain are the topics John Mandrola, MD, covers in today\\u2019s podcast. To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I \\u2013 ESUS

Anticoagulation May Benefit Stroke Patients With LV Dysfunction https://www.medscape.com/viewarticle/961815

- Left Ventricular Dysfunction Among Patients With Embolic Stroke of Undetermined Source and the Effect of Rivaroxaban vs AspirinA Subgroup Analysis of the NAVIGATE ESUS Randomized Clinical Trial

https://jamanetwork.com/journals/jamaneurology/article-abstract/2785030

- Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source

https://www.nejm.org/doi/10.1056/NEJMoa1802686

- Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source

https://www.nejm.org/doi/10.1056/NEJMoa1813959

II \\u2013 CAC

CAC Score 0 Unreliable to Rule Out Stenosis in Younger Patients https://www.medscape.com/viewarticle/961801

- Association of Age With the Diagnostic Value of Coronary Artery Calcium Score for Ruling Out Coronary Stenosis in Symptomatic Patients https://jamanetwork.com/journals/jamacardiology/fullarticle/2785586

- The Case Against Coronary Artery Calcium Scoring for Cardiovascular Disease Risk Assessment

https://www.aafp.org/afp/2019/1215/p734.html

III \\u2013 Takotsubo Cardiomyopathy

Broken Heart Syndrome: On the Rise, Especially in Women 50-74

https://www.medscape.com/viewarticle/961307

- Sex\\u2010 and Age\\u2010Based Temporal Trends in Takotsubo Syndrome Incidence in the United States

https://www.ahajournals.org/doi/10.1161/JAHA.120.019583

IV- Chest Pain Guidelines

AHA/ACC Issues First Comprehensive Guidance on Chest Pain

https://www.medscape.com/viewarticle/961806

- 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: Executive Summary:\\xa0A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines https://www.jacc.org/doi/10.1016/j.jacc.2021.07.052

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Questions or feedback, please contact news@medscape.net