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Diffuse Intrinsic Pontine Glioma, or DIPG, is a rare but particularly aggressive and hard-to-treat tumor. Ranjit Bindra MD, PhD, a practicing radiation oncologist at the Yale School of Medicine and Associate Professor of Therapeutic Radiology, is leveraging his translational research and clinical experience to find new ways to treat this cancer. 3:18 – On the use of radiation to treat cancer patients: “…really the most exciting research on the horizon is trying to understand which particular tumors—what types of mutations in the DNA of those tumors—make them more sensitive to treatments that have radiation therapy.” 6:19 – On his research into combining drugs with radiation: “We are very interested in finding tumor mutations—the actual mutations that drive those cancers. We try to find ways to target them with novel drugs so that when we combine them with radiation, it’s sort of a 1-2 punch.” 10:11 – On Diffuse Intrinsic Pontine Glioma, or DIPG. What is it? What are the current treatments? Why aren’t they working? What is the exciting new finding by his team? 22:09 – On how his lab sees a path towards a clinical trial with DIPG patients 26:43 – On the impact of American Cancer Society funding on his work 28:23 – A message he’d like to share with patients