Engineering Recombinantly Expressed Antiviral Lectins
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Cyanovirin-N, or CV-N for short, is a broadly binding molecule to glycopeptides and glycan structures on viral envelope spikes, which allows for screening of these structures by protein-interaction based sensor technologies.
Dr. Irene Maier, Lecturer at the Medical University of Vienna, Austria, examines the molecular understanding of immune diseases. Maier has designed new antiviral CV-N variants and measured their binding constants to glycoproteins exposed at the surface of immune-stimulating cells, which has the potential to revolutionize treatments against viral infections.
Find out more about Irene's work on ResearchGate
Read the original research: https://www.jove.com/de/t/63541/engineering-antiviral-agents-via-surface-plasmon-resonance