Shortages of lifesaving drugs\u2014the result of failures at every step of complex supply chains\u2014have far-reaching impacts on patients, providers, and the broader field of medicine. Hopkins oncologist Dr. Amanda Nickles Fader and policy researcher Dr. Mariana Socal talk with Dr. Josh Sharfstein about the broader systems problem resulting in the shortages of a vast range of drugs and how it\u2019s changing treatment protocols and the patient experience.