Younger, but not older, brains are poised at a critical point of functional activity

Published: March 29, 2021, 1:03 a.m.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.17.047233v1?rss=1 Authors: Weistuch, C., Mujica-Parodi, L. R., Amgalan, A., Dill, K. A. Abstract: Aging is associated with significant changes in communication between brain regions, yet the principles governing these changes are poorly understood. Here, we examined the role of age-related glucose hypometabolism by adapting functional MRI data to the Ising model. We found that younger, but not older, brains are poised at a critical point, facilitating switching between specific patterns of integrated and segregated activity, and consistent with decreased energy availability. Copy rights belong to original authors. Visit the link for more info