Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.24.219097v1?rss=1 Authors: Acera Mateos, P., Balboa, R. F., Easteal, S., Eyras, E., Patel, H. R. Abstract: Viral co-infections occur in COVID-19 patients, potentially impacting disease progression and severity. However, there is currently no dedicated method to identify viral co-infections in patient RNA-seq data. We developed PACIFIC, a deep-learning algorithm that accurately detects SARS-CoV-2 and other common RNA respiratory viruses from RNA-seq data. Using in silico data, PACIFIC recovers the presence and relative concentrations of viruses with >99% precision and recall. PACIFIC accurately detects SARS-CoV-2 and other viral infections in 63 independent in vitro cell culture and patient datasets. PACIFIC is an end-to-end tool that enables the systematic monitoring of viral infections in the current global pandemic. Copy rights belong to original authors. Visit the link for more info