05:50 Why NAD+
10:11 Cell waste not, want not
13:55 Why NAD decreases with age
15:20 CD38 consumption of NAD+
17:33 Micro RNA and NAD decrease
25:30 Negative feedback loops
26:30 Possible supplementation to boost NAD+
32:10 Cellular timing
33:50 NAD and fasting/exercise
37:38 Micro RNA and senescence
39:15 Cellular sensing and fasting
41:40 mTOR and meat intake
44:50 Limitations of dietary studies
51:30 Diet and tribalism
53:52 NAD boosters, the next revolution?
57:35 Timing of supplementation
01:01:20 Novel outcomes of NAD+
01:05:10 NAD and sleep cycles/circadian rhythm
01:10:10 Is sacrificing sleep necessary for humanity?