Episode 2 - Metformin
In the next step in their biology of ageing odyssey, Terry and Jahan take a dive into the wild world of metformin. Show notes:
Metformin through history - 2:10
Alternative medicine vs medicine - 3:50
Metformin in Diabetes and other diseases: 7:20
Mechanism of action: 09:10
Link to exercise and fasting: 19:00
TAME Trial: 22:00
Do we take metformin?: 27:45
Inhibiting the effects of excercise: 33:30
Side effects: 39:00
Mechanism of COVID ARDS protections: 40:00
Repurposing medicines for longevity: 42:30
Notes on Rapamycin: 43:50
The sauna: 48:00
Unwhelmed by telomeres: 52:20
Lobsters: 53:20