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The co-hosts of ISGP's "The Forum" discuss the application and governance of precision medicine at home and abroad, case-studying the United States' Precision Medicine Initiative (PMI). This podcast was recorded LIVE during Session 6 of NextGenMed: Precision Medicine, a virtual conference on disease predisposition, diagnostics, and treatment hosted by ISGP's "The Forum," Penn Center for Precision Medicine, and medical students at Drexel and Temple Universities on March 27, 2018. For more information on this virtual event, please visit www.facebook.com/isgpforum. Socialize with science on Twitter using @ISGPforum with #ISGPforum, and read the policy position paper and debate summary associated with this episode at the Institute on Science for Global Policy's website: www.scienceforglobalpolicy.org. Disclaimer: The ISGP is a nonprofit organization that does not lobby for any position except rational thinking. Podcasts reflect the views expressed by conference participants. ISGP conferences follow an unique debate-and-caucus format. Distinguished scientists write 3-page policy position papers, then engage in 90 minutes of intensive debate with invited subject matter experts, policy makers, and other stakeholders collectively known as “the debaters.” Following the debates, participants engage in small, moderated caucus sessions to identify areas of consensus and actionable next steps. All conference participants then reconvene for a plenary session to compare the outcomes from each caucus group. For more information, please visit www.scienceforglobalpolicy.org.