Frances Arnold

Published: Sept. 20, 2022, 4 a.m.

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Nobel Prize winning chemist Frances Arnold left home at 15 and went to school \\u2018only when she felt like it\\u2019. She disagreed with her parents about the Vietnam war and drove big yellow taxis in Pittsburgh to pay the rent.\\nDecades later, after several changes of direction (from aerospace engineer to bio-tech pioneer), she invented a radical new approach to engineering enzymes. Rather than try to design industrial enzymes from scratch (which she considered to be an impossible task), Frances decided to let Nature do the work. \\u2018I breed enzymes like other people breed cats and dogs\\u2019 she says.

While some colleagues accused her of intellectual laziness, industry jumped on her ideas and used them in the manufacture of everything from laundry detergents to pharmaceuticals.\\nShe talks to Jim Al-Khalili about her journey from taxi driver to Nobel Prize, personal tragedy mid-life and why advising the White House is much harder than doing scientific research.

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