The Role of IgA with the SARS-COV-2 Infection

Published: July 20, 2020, 4 p.m.

On today’s episode we talk with Dr. Marie C. Bene. She is a professor of immunology and hematology at Centre Hospitalier Universitaire de Nantes, France. Today we discuss her latest research on IgA and SARS-COV-2, the challenges in vaccine development for COVID-19, and how her principles are being used in current investigations.

Dr. Marie C. Bene has experience in work at the Centre Hospitalier Universitaire de Nancy as well, as both a PUPH as well as a MCUPH. Dr. Bene’s published works include papers about DNA extraction for multiplex diagnosis of factor V Leiden and prothrombin gene variants, ligand plasma levels and its lack of impact on acute leukemia patients, as well as papers on allotransplants in lymphoma patients.

Talking points:

  • Introduction (00:00)
  • Dr. Marie C. Bene’s latest publication (00:54)
  • The relation of IgA with the SARS-COV-2 infection (02:20)
  • Uses of Dr. Bene’s findings, for detection and cure (05:34)
  • Current investigations utilizing Dr. Bene’s principles (07:05)
  • Takeaway message from Dr. Bene’s work (07:35)
  • The relevance of testing issues with the process of development of a vaccine (08:27)
  • The biggest challenges in vaccine development (09:10)
  • Conclusion (09:49)

Resources:

“Good IgA bad IgG in SARS-CoV-2 infection?"
Clinical Infectious Diseases. 2020 April 11.
https://pubmed.ncbi.nlm.nih.gov/32280952/