TWiV 887: Bonfire of the monocytes
TWiV explains why this season\u2019s influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19.
Hosts:\xa0Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld
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Links for this episode- Seasonal influenza vaccine effectiveness (MMWR)
- Properties of a dominant H3N2 variant (bioRxiv)
- Scott Henley on influenza vaccine growth in eggs (TWiV 480)
- Fc receptor dependent entry of SARS-CoV-2 into monocytes (Nature)
- Timestamps by Jolene. Thanks!
Dickson \u2013 Ketanji Brown Jackson confirmed to US Supreme Court
Amy \u2013 Some threats just keep coming in waves
Rich \u2013 Lady Bird Johnson Wildflower Center
Vincent \u2013 Martijn Doolaard
Ann \u2013 Immunological memory to SARS-CoV-2 infection and vaccines
Chris \u2013 Isoplexis
Intro music is by\xa0Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv