TWiV 734: Weiss hath no furin like a virus scorned
Susan Weiss returns to TWiV to discuss coronavirus entry into cells and the role of spike protein cleavage by proteases, why lab escaped hypotheses for SARS-CoV-2 are unlikely, and modulation of innate immune responses during infection.
Hosts:\xa0Vincent Racaniello, Rich Condit, Alan Dove, Brianne Barker, and Amy Rosenfeld
Guest: Susan Weiss
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Links for this episode- CoV pathogenesis in CNS (J Neuro Pharm)
- SARS-CoV-2 induces dsRNA-mediated innate responses (bioRxiv)
- Screen of FDA-approved drugs (J Viral)
- Letters read on TWiV 735
- Timestamps by Jolene. Thanks!
Brianne \u2013 Tiktok of How mRNA Vaccines Work
Alan \u2013 Dark
Rich \u2013 Unmixing Color Machine (Ultra Laminar Reversible Flow) \u2013 Smarter Every Day 217
Amy \u2013 MOMA Calder exhibit, reviewed in NYTimes
Vincent \u2013 Ripple Training (free YouTube channel)
Ruth \u2013 100 million year old seafloor bacteria resuscitated
Iradis \u2013 Linda Zall, CIA spy for science
Intro music is by\xa0Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv