BROADCASTS.com

Published: Nov. 29, 2015, 3:02 p.m.

Hosts:\xa0Vincent Racaniello,\xa0Alan Dove, and\xa0Kathy Spindler

\n

For\xa0a\xa0TWiV Thanksgiving, Vincent, Alan, and Kathy trace the feud\xa0over genome editing, a new virus discovered in human blood, and the origins of hepatitis A virus.

\nLinks for this episode\n

\n
• Battle over\xa0genome editing\xa0(Wired) 10:05
\n
• First description\xa0of CRISPR in\xa0E. coli\xa0(J Bacteriol) 14:00
\n
• Cas genes\xa0identified (Mol Micro) 14:20
\n
• CRISPR-Cas provides\xa0immunity to bacterial viruses\xa0(Science) 15:35
\n
• Cas9-crRNA complex\xa0mediates DNA cleavage (PNAS) 16:55
\n
• Dual\xa0RNA-guided DNA endonuclease\xa0in bacterial immunity (Science) 17:50
\n
• Genome engineering\xa0using CRISPR/Cas (Science) 18:50
\n
• Cpf1\xa0endonuclease (Cell) 23:10
\n
• Classification\xa0of CRISPR/Cas systems (Nat Rev Micro) 23:50
\n
• Summit on\xa0gene editing\xa021:25
\n
• Novel human virus\xa0in transfusion recipients (mBio) 27:00
\n
• Origins of\xa0hepatitis A virus\xa0in small mammals (PNAS) 55:05
\n
• Image\xa0credit
\n
• Letters read\xa0on TWiV 365 7:00, 1:20:35
\n

\n

This episode is sponsored by\xa0ASM Microbe,\xa0ASM Biodefense, and the\xa032nd Clinical Virology Symposium. (1:10,\xa01:18:30)

\nWeekly Science Picks 1:36:30\n

Kathy -\xa0Tardigrade genome sequence\xa0(video)
Alan\xa0-\xa0XKCD on Gates polio eradication site
Vincent\xa0-\xa0Lifting the Impenetrable Veil\xa0by Charles Calisher

\nListener\xa0Picks\n

Judi\xa0-\xa0Jennifer Doudna's Ted Talk
Ramon\xa0-\xa0Map of the Sky

\n

Send your virology questions and comments to twiv@twiv.tv