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Vincent, Dick, and Alan review a new macaque model for HIV-1 infection, a possible role for Epstein-Barr virus in multiple sclerosis, accidental release of H5N1 by a vaccine company, resistance of frogs to virus infection, and extreme virology - the biggest and smallest viruses and viral genomes.

Links for this episode:

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• Harold Varmus on The Daily Show
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• Macaque model for HIV-1 infection (photo of pig-tailed macaque)
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• Possible role of Epstein-Barr virus in multiple sclerosis
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• Accidental distribution of H5N1 influenza virus by pharmaceutical company
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• Major histocompatibility class I marker and frog resistance to viral infection
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• Smallest virion and DNA genome: Circovirus
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• Largest virion and DNA genome: Mimivirus
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• Biggest RNA genome: (we forgot to mention on the show!) Coronavirus SW1
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• List of viral genome lengths at NCBI
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• Sputnik virophage
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• Papers for Macintosh and iPhone
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Science blog of the week: H5N1 by Croft
Science podcast pick of the week: MicrobeWorld video
Science book of the week: Autism\u2019s False Prophets by Paul A. Offit, MD (podcast with Dr. Ginger Campbell)