TWiV 1133: Gain of function makes us safer
TWiV reviews cases of measles in Brooklyn NY and Washington DC, stalling of global childhood vaccination, licenses H5N1 vaccines protect against circulating strains, viruses traveling without passports. OC43 SARS-CoV- 2 spike replacement virus as an improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays, and deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex.
Hosts:\xa0Vincent Racaniello,\xa0Dickson Despommier,\xa0Alan Dove,\xa0Rich Condit, and\xa0Kathy Spindler
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Links for this episode- MicrobeTV Discord Server
- Measles in\xa0Brooklyn NY\xa0(ABC)
- Measles in\xa0Washington DC\xa0(DC Health)
- Global\xa0childhood immunization stalls\xa0(WHO)
- Licensed H5N1 vaccines\xa0protect against circulating strains (Nat Med)
- Viruses moving\xa0without passports\xa0(European CDC)
- OC42-SARS-CoV-2\xa0replacement spike virus\xa0(PNAS)
- Deep mutational scanning of\xa0Lassa virus glycoprotein\xa0(Immunity)
- Letters read\xa0on TWiV 1133
- Timestamps by\xa0Jolene. Thanks!
Dickson\xa0\u2013\xa0Elemental sulfur found on Mars
Kathy\xa0\u2013\xa0Lennette Lectures at ASV, including\xa0Gail Wertz, ASV 2024
Rich\xa0\u2013\xa0Electricity maps\xa0(Opinions:\xa0Nuclear Waste Is Misunderstood;\xa0Should We Be Worried About Nuclear Waste?)
Alan\xa0\u2013\xa0Nature\xa0sent an investigative reporter\xa0to a predatory conference
Vincent\xa0\u2013\xa0Coal-filled trains are likely sending people to the hospital
Intro music is by\xa0Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.