TWiV 1128: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the fourth US case of H5N1 human infection and reminds the audience of the definition of \u201cpasteurization\u201d before reviewing the recent statistics on SARS-CoV-2 infection, where to find PEMGARDA, the effectiveness of molnupiravir and dexamethasone, convalescent plasma, what to do when healthcare workers succumb to SARS-CoV-2 infection, how an EEG can be used to look for signatures of cognitive decline after SARS-CoV-2 infection and what we observed 2 years following SARS-CoV-2 infection for tissue-resident T cell and viral RNA persistence.
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Links for this episode- Fourth case human infection\xa0associated with an ongoing multistate outbreak of A(H5N1) (CDC)
- Human H5N1 in Colorado and thedefinition\xa0of pasteurization (CIDRAP)
- Is\xa0\u201craw\u201d\xa0milk more risky than pasteurized (Annenberg Public Policy Center)
- COVID-19\xa0national trend\xa0(CDC)
- COVID-19\xa0deaths\xa0(CDC)
- Winter, spring, summer and fall\xa0COVID-19 surges? (CDC)
- Where\xa0to get pemgarda (Pemgarda)
- Unable to access Pemgarda, gotta\xa0call Daniel\xa0(microbeTV)
- CDC Quarantine\xa0guidelines (CDC)
- Early phase\xa0of SARs-CoV-2 infection (COVID.gov)
- NIH\xa0COVID-19 treatment guidelines (NIH)
- Infectious Disease Society guidelines\xa0for treatment and management (ID Society)
- Drug interaction\xa0checker\xa0(University of Liverpool)
- Molnupiravir\xa0safety\xa0and efficacy (JMV)
- Molunpiravir\xa0works: reduces hospitalizations and deaths due to COVID-19 and all-cause mortality (CID)
- Convalescent plasma recommendation for\xa0immunocompromised\xa0(ID Society)
- What do when your\xa0heathcare provider\xa0is infected with SARS-CoV-2 (CDC)
- Managing healthcare staffing\xa0shortages\xa0(CDC)
- Steroids,dexamethasone\xa0at the right time (OFID)
- Benefits of\xa0dexamethasone,\xa0reversal of monocyte dysfunction for severe COVID-19 (Cell)
- Anticoagulation\xa0guidelines (hematology.org)
- EEG signatures for\xa0cognitive decline\xa0after SARS-CoV-2 infection (BMC Medicine)
- Tissue resident T-cells and viral RNA\xa02 years after\xa0SARS-CoV-2 infection (Science Translational Medicine)
- Contribute to our\xa0Floating Doctors\xa0fundraiser
- Letters read\xa0on TWiV 1128
- Dr. Griffin\u2019s COVID treatment summary (pdf)
- Timestamps by\xa0Jolene. Thanks!
Intro music is by\xa0Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv