TWiV 1092: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing new vaccine guidelines released by the advisory committee on immunization practices, and reviews the CDC guidelines for quarantine/ isolation following SARS-CoV-2 infection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, the role of IFN-g in long COVID, if the brain-blood-barrier is compromised in long COVID, meaning of persistent community SARS-CoV-2 RNA findings, and the effects of hyperbaric oxygen on post COVID neurocognition.
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Links for this episode- Respiratory\xa0disease\xa0surveillance (CDC)
- RSV\xa0surveillance\xa0 (CDC)
- RSV\xa0national\xa0trend (CDC)
- RSV\xa0vaccination stats\xa0(CIDRAP)
- Influenza/flu\xa0surveillance\xa0\xa0(CDC)
- Influenza/flu\xa0map\xa0(CDC)
- COVID-19\xa0\xa0hospital\xa0admissions (CDC)
- COVID-19\xa0national\xa0trend (CDC)
- COVID-19\xa0wastewater\xa0testing (biobot)
- Variant\xa0tracker (CDC)
- Variant hospital\xa0admissions (CDC)
- ACIP\xa0COVID vaccination for seniors\xa0recommendations (CIDRAP)
- Additional vaccine doses for\xa0older adults\xa0(CDC)
- Evidence based advice\xa0from the ACIP (CDC)
- State mandates\xa0did NOT\xa0influence primary vaccination rates only boosters (PNAS)
- No nOPV2? (CDC)
- CDC Quarantine\xa0guidelines (CDC)
- To rebound or to\xa0not rebound\xa0(MMWR)
- Know your\xa0COVID-19 tools (ESMED)
- How to pay\xa0for Paxlovid (PAXCESS)
- Molnupiravir\xa0safety\xa0and efficacy (JMV)
- Molunpiravir plus antibody therapy\xa0for at-risk outpatients (Nat Comm)
- Convalescent plasma recommendation for\xa0immunocompromised\xa0(IDSociety)
- Steroids,\xa0dexamethasone\xa0at the right time (OFID)
- Anticoagulation\xa0guidelines (hematology.org)
- Spontaneous release\xa0of IFN-g in Long COVID (Science Advances)
- Blood-brain-barrier compromise\xa0in long COVID associated cognitive impairment (Nat Neuroscience)
- Persistent community\xa0SARS-CoV-2 RNA (Nature)
- Hyberbaric oxygen therapy\xa0improves post COVID neurocognition (Scientific Reports)
- Medical study questionnaire,\xa0the SHORT form\xa0(Brandeis)
- Long term effects\xa0of hyperbaric oxygen post COVID (Scientific Reports)
- Contribute to our\xa0ASTMH fundraiser at PWB
- Letters\xa0read\xa0on TWiV 1092
- Dr. Griffin\u2019s COVID treatment summary (pdf)
- Timestamps by\xa0Jolene. Thanks!
Intro music is by\xa0Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv