TWiP 178: The shadowlands of medicine
The Knights of the TWiP solve the case of the Man Who Lost Weight, and discuss a Plasmodium protein kinase that is a malarial drug target.
Hosts:\xa0Vincent Racaniello, Dickson Despommier, and\xa0Daniel Griffin
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- Protein kinase as malaria drug target (Science)
- Hero: Myron Schultz
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Case Study for TWiP 178Eastern border of Uganda with Kenya, in mountains. Drinking water from nearby stream. Two young boys come to clinic, without parents. Sent in by grandmother because 1 yo brother has been passing worms. Long, white, flat. Shown photos in PD7, pinkish worm, 8 inches long, round. He points to those, what he has been seeing in brother\u2019s stool. 1 year old seems small, protuberant abdomen; brother small for stated age, bit of protuberant belly. Diet: high carbohydrate, flour deep fried; yams; cabbage; some rice; soybeans; pumpkin; bananas.
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Music by\xa0Ronald Jenkees