TWiP 143: There's a lot of worms out there
The TWiPians solve the case of the Woman With Anemia, Eosinophila, and a Worm in Her Intestine, and discuss a study on the function and druggability of two malarial aspartate proteases.
Hosts:\xa0Vincent Racaniello, Dickson Despommier, and\xa0Daniel Griffin
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Links for this episode:- Malaria plasmepsins involved in invasion and egress (Science)
- Letters read\xa0on TWiP 143
From 1990s seen by a colleague, boy late teens, initially presented to ER in US chief complaint, visual disturbances and itching preventing sleep. Immigrated from Oaxaca, searching for work. Lived in modest dwelling with dirt floors, no running water, got from local river. Reports dogs, farm animals, many insects. On exam: tender nodules on head, skin irritated from scratching, small punctate lesions on right cornea. Is referred to specialists. Ophthalmologist called in, referred for further diagnostics.
Send your case diagnosis, questions and comments to\xa0twip@microbe.tv
Music by\xa0Ronald Jenkees