TWiP 100: Driving past a milestone
Hosts:\xa0Vincent Racaniello,\xa0Dickson Despommier, and Daniel Griffin
\nThe TWiP trifecta solves the case of the\xa0Woman from Bolivia with Belly Pain, and discuss a\xa0method for population modification of malaria mosquitoes using a\xa0Cas9-mediated driver gene.
\nLinks for this episode:\n- \n
- Cas9-mediated drive\xa0for population modification of malaria mosquito (PNAS) \n
- FAQ: Gene drives\xa0(pdf) \n
- Image credit \n
- Letters read\xa0on TWiP\xa0100 \n
This week's case is a\xa027 yo female, native NY, referred to outpatient at CU after seeing OBGYN, told had seen worms in stool and underwear. Inch or two in length, pale white, round, moving, 2-3 weeks of constant abdominal bloating. Sexually active. No particular diet. Travel: works for NGO, refugee camp in Ethiopian-Sudan border, southern Sudan. Last visit month ago. Noticed worms when she got back from last trip. Eats what local people eat. Raw food popular there: kitfo, raw steak tartare, with melted butter. Made from local beef. Did not take malaria prophylaxis, did not avoid local water, does wear sandals. College graduate. Nothing remarkable in family. CBC, liver, metabolic: all normal. Stool not normal: loose, no mucus or blood.
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\nSend your questions and comments (email or mp3 file) to\xa0twip@microbe.tv