A must-watch deep dive into some science!\nVaccine expert Dr. Paul Offit is less than impressed with evidence to support the Omicron BA.4/5 "bivalent" booster shots now rolling out for everyone 12 and older. We also talk polio and monkeypox and flu \U0001f44d\nVideo: https://zdoggmd.com/paul-offit-10/\nTopics & Timestamps:\n00:00 Intro\n1:10 A brief history of the Covid vaccines, groups that benefit from boosting\n5:12 Incubation periods and vaccination "goals," preventing infection vs. severe disease\n10:54 Bivalent vaccine, the FDA's EUA approach, crucial dosing issues (ancestral strain vs. bivalent)\n17:15 BA.4/5 booster immunogenicity data (or lack thereof), mouse data & vax safety profile\n21:40 Why Paul himself would pass on the new booster, incubation periods, why Covid zero is a fantasy\n24:28 Paul's "perfect" bivalent vaccine\n25:37 Yearly targeted boosters, myocarditis and the Thai children's study\n28:39 BA.4/5: MIS-C, boosters & long Covid, data from JAMA's Italian study\n31:28 Comparing BA.4/5 & the yearly flu vax, timing of the yearly flu shot\n38:45 Polio's resurgence, injected inactivated vs. live oral polio vaccines, the role of sanitation\n48:05 Monkeypox and a history of smallpox vaccines\n56:43 Reflection w/Dr. Offit: what\xa0he's gotten right, what he's gotten wrong and where to go from here\n1:01:57 Final thoughts\n\nVideo show archive, audio podcasts, music parodies, Supporter Tribe membership options, merch, social media, and email contact form:\xa0https://lnk.bio/zdoggmd\n\n\nSupport us with a 1-time donation and get a personal email response from me: https://www.paypal.com/paypalme/zdoggmd\n\n\nMore about Dr. Z:\xa0https://zdoggmd.com/about-z/\n\n\n\nLearn more about your ad choices. Visit megaphone.fm/adchoices