New Science Could Sharpen Crispr's Gene-Editing Scalpel

Published: Oct. 27, 2017, 8:12 a.m.

b'Stay on target. That\\u2019s the mantra you hear in labs and biotech companies around the world as they snip away at DNA. All the techniques for gene editing\\u2014from the famous Crispr-Cas9 to the older TALENs and zinc-finger nucleases\\u2014share a problem: Sometimes they don\\u2019t work. Which is to say, they have \\u201coff-target effects,\\u201d changing a gene you don\\u2019t want changed or failing to change a gene that you do. And DNA is not something you want poorly rewired.\\nLearn more about your ad choices. Visit podcastchoices.com/adchoices'