From Junk DNA to an RNA Revolution
b'What the heck is "junk DNA"? \\n\\nIn this episode, a16z General Partner Jorge Conde and Bio Eats World host Hanne Winarsky talk to Professor Rick Young, Professor of Biology and head of the Young Lab at MIT\\u2014all about "junk" DNA, or non-coding DNA. \\n\\nWhich, it turns out\\u2014spoiler alert\\u2014isn\\u2019t junk at all. Much of this so-called junk DNA actually encodes RNA\\u2014which we now know has all sorts of incredibly important roles in the cell, many of which were previously thought of as only the domain of proteins. This conversation is all about what we know about what that non-coding genome actually does: how RNA works to regulate all kinds of different gene expression, cell types, and functions; how this has dramatically changed our understanding of how disease arises; and most importantly, what this means we can now do\\u2014programming cells, tuning functions up or down, or on or off. What we once thought of as "junk" is now giving us a powerful new tool in intervening in and treating disease\\u2014bringing in a whole new category of therapies.'