Silencing an ALS Gene Tim Miller
How could a gene that causes one type of ALS be switched off? In episode 87, Tim Miller from the Washington University in St. Louis discusses his research into therapies that target the single strands of DNA or RNA which cause many cases of amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease. His article \u201cPhase 1\u20132 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS\u201d was published with multiple co-authors on July 9th 2020 in the New England Journal of Medicine.\xa0\n\nSilencing an ALS Gene - Tim MillerSilencing an ALS Gene - Tim MillerSilencing an ALS Gene - Tim Miller\xa0Silencing an ALS Gene - Tim MillerSilencing an ALS Gene - Tim MillerSilencing an ALS Gene - Tim Miller {{svg_share_icon}}Click bottom of waveform to add your commentsSubscribe: iTunes | Google Podcasts | Google Play | Spotify | RSS jQuery(document).ready(function ($){var settings_ap7669 = { design_skin: "skin-wave" ,autoplay: "off",disable_volume:"default" ,loop:"off" ,cue: "on" ,embedded: "off" ,preload_method:"metadata" ,design_animateplaypause:"default" ,skinwave_dynamicwaves:"off" ,skinwave_enableSpectrum:"off" ,skinwave_enableReflect:"on",playfrom:"off",default_volume:"default",disable_scrub:"off",soundcloud_apikey:"" ,skinwave_comments_enable:"on",settings_php_handler:window.ajaxurl,skinwave_mode:"alternate",skinwave_wave_mode:"canvas",pcm_data_try_to_generate: "on","pcm_notice": "off","notice_no_media": "on",design_color_bg: "111111",design_color_highlight: "FF4C65",skinwave_wave_mode_canvas_waves_number: "3",skinwave_wave_mode_canvas_waves_padding: "1",skinwave_wave_mode_canvas_reflection_size: "0.25",skinwave_wave_mode_canvas_mode:"normal",preview_on_hover:"off",skinwave_comments_playerid:"7669",embed_code:""\n,enable_embed_button:"on",php_retriever:"https://www.parsingscience.org/wp-content/plugins/dzs-zoomsounds/soundcloudretriever.php" }; try{ dzsap_init(".ap_idx_7669_120",settings_ap7669); }catch(err){ console.warn("cannot init player", err); } }); \n\xa0\nWebsites and other resources\n\n\t\n\n\tNEJM editorial on Tim's study\n\tTim's lab website\n\tVideo of Tim discussing new therapies for ALS:\n\n\n\n\nhttps://www.youtube.com/watch?v=4I0asIWLCxM\n\xa0\n\n\xa0\nSelect media and press\n\xa0\nEurekAlert | WBUR | Physician's Weekly | Futurity | Medscape | 2 Minute Medicine\n\xa0\n\n div.altmetric-embed {flex-shrink: 2; -webkit-flex-shrink: 2;} \n\xa0\n\ufeff\n\nBonus Clips\n\n\nClips available include ...\nFull episode with available download\nMore coming soon\n\n\n\U0001f50a Access bonus content here.\n\nSupport us for as little as $1 per month at Patreon. Cancel anytime.\nWe\u2019re not a registered tax-exempt organization, so unfortunately gifts aren't tax deductible.\nHosts / Producers\nRyan Watkins &\xa0 Doug Leigh\nHow to Cite\nWatkins, R., Leigh, D., & Miller, T.. (2020).\xa0Parsing Science - Silencing an ALS Gene. doi: 10.6084/m9.figshare.13232651\n\xa0\nMusic\nWhat\u2019s The Angle? by Shane Ivers\nTranscript\nComing soon!