Time scale separation of information processing between sensory and associative regions

Published: Oct. 24, 2020, 8:02 a.m.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.23.350322v1?rss=1 Authors: Sorrentino, P., Rabuffo, G., Rucco, R., Baselice, F., Troisi Lopez, E., Liparoti, M., Quarantelli, M., Sorrentino, G., Bernard, C., Jirsa, V. Abstract: Behavioral responses are brain-state dependent and rely on the coordinated activity of brain areas. Their exchange of information within the network can be represented as functional links establishing a spatiotemporal pattern, evolving over time and scales. Network neuroscience offers useful tools that may guide our understanding of these patterns organisation. Here we used source-reconstructed Magnetoencephalography signals from a large healthy cohort, and estimated a link-specific time-scale as the information decay-time. Their distribution allowed the identification of two anatomically distinct and functionally coherent networks. Rapidly-decaying links define a fast-updating networK (FUN), which includes regions typically involved in the processing of external stimuli. Slow-decaying links define a slow-updating network (SUN), which comprises hierarchically higher regions, classically involved in the integration of such stimuli. Finally, we show that only a subset of the brain regions belong to both subnetworks, which we name the multi-storage core (MSC). The MSC is hypothesized to play a role in the communication between the (otherwise) temporally segregated subnetworks. Copy rights belong to original authors. Visit the link for more info