Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.11.078915v1?rss=1 Authors: Cymerblit-Sabba, A., Stackmann, M., Williams Avram, S., Granovetter, M. C., Cliz, N. I., Pereira, F., Smith, A. S., Song, J., Lee, H.-J., Young, W. S. Abstract: Recognition memory, often compromised in psychiatric disorders, is a major component of declarative memory, which permits the realization that an event, object or social subject has been previously encountered. The CA2 region of the dorsal hippocampus (dCA2) is involved in social memory and responds to novel objects, in time and space. However, it remains unclear how these neurons encode either social or inanimate object recognition. Here, we show that in dCA2, encoding of social recognition memory entails suppression of pyramidal neurons activity leading to a sparse representation of the familiar conspecific. We discuss the neural coding scheme by which dCA2 pyramidal neurons contribute to social memory. Copy rights belong to original authors. Visit the link for more info