Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.26.114488v1?rss=1 Authors: Iandolo, R., Semprini, M., Mantini, D., Buccelli, S., Sona, D., Avanzino, L., Chiappalone, M. Abstract: Recent studies provided novel insights into the meso-scale organization of the brain, highlighting the co-occurrence of different structures: classic assortative (modular), disassortative and core-periphery. However, the spectral properties of the brain meso-scale remain unexplored. To fill this knowledge gap, we investigated how this meso-scale structure is organized across the frequency domain. We analyzed the resting state activity of healthy participants with source-localized high-density electroencephalography signals. Then, we inferred the community structure using weighted stochastic block-modelling to capture the landscape of meso-scale structures across the frequency domain. Despite meso-scale modalities were mixed over the entire spectrum, we found a selective increase of disassortativity in the delta/theta bands, and of core-peripheriness in the low/high gamma bands. We observed, for the first time, that the brain at rest shows frequency-specific meso-scale organizations supporting spatially distributed and local information processing, shedding new light on how the brain coordinates information flow. Copy rights belong to original authors. Visit the link for more info