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Before March 2020, a search for the keyword \u201ccoronavirus\u201d would have turned up zero results on Mathematica\u2019s website. Now the word and its sibling, COVID-19, appear in more than two dozen pages about contact tracing, wastewater testing, disease modeling, workforce planning, and more. \n\nOwing to the wide-ranging effects of the novel coronavirus, Mathematica\u2019s experts have sprung into action to understand its implications for primary care, child protective services, behavioral health, remote learning in K-12 education, surging unemployment among workers with disabilities, and food insecurity among children who no longer have access to daily school meals. Although the pandemic is touching almost every conceivable area of public wellbeing, it started as a public health threat and has galvanized Mathematica\u2019s nearly 600 health care and policy experts, researchers, technologists, data scientists, clinicians, survey experts, and program design and management experts to apply their skills and creativity in responding to the crisis. \n\nFor this episode of On the Evidence, Chris Trenholm, the managing director of health at Mathematica, discusses the impacts of COVID-19 on public health, what the pandemic reveals about the social determinants of health and racial disparities in health care, and how Mathematica\u2019s partners in government, philanthropy, and the private-sector are developing new tools and strategies in light of the pandemic.