13 August 2013: In this episode, Dr. Robert Dellavalle speaks with Dr. Hywel Williams, from Nottingham University, about clinical trials and systematic reviews. Randomized controlled clinical trials remain the best method for minimizing bias when evaluating dermatological treatments. Systematic reviews of these trials organize the entire body of evidence while minimizing bias so that policy makers and guideline developers can base their recommendations on the appropriate strength and level of evidence.