04 January 2013: Join presenter Dr. Jeffrey Dunn as he speaks with Dr. Ruby Ghadially about the past 25 years of epidermal stem cell research. Understanding of epidermal stem cell biology has evolved rapidly as techniques to visualize distribution of stem cells and progeny have improved. However, significant challenges remain, including defining molecular markers for stem cells, determining the locations and contributions of different stem cell niches, and mapping regulatory pathways of epidermal stem cell proliferation and differentiation.