Ep 47 -Nobel prize winning gene editing technology CRISPR modified for sensing!
Have you heard of CRISPR, the ground breaking gene editing technology? The one that got Emmanuelle Charpentier and Jennifer A. Doudna the Nobel Prize in Chemistry in 2020? This technology was repurposed by researchers from Fudan University to detect cell free DNA! Tune in to learn more!
\nReferences:
\nYang, B.; Kong, J.; Fang, X. Programmable CRISPR-Cas9 microneedle patch for long-term capture and real-time monitoring of universal cell-free DNA. Nat Commun 2022, 13, 1-16.
\nXue, C.; Greene, E. C. DNA Repair Pathway Choices in CRISPR-Cas9-Mediated Genome Editing. Trends in Genetics 2021, 37, 639-656.
\nYoung, L. S.; Yap, L. F.; Murray, P. G. Epstein-Barr virus: more than 50 years old and still providing surprises. Nat Rev Cancer 2016, 16, 789-802.
\nIntro/Outro music:
\n