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I am thrilled to have Dr. Nick Norwitz, a researcher-educator on a mission to mainstream metabolic health, joining me today. Dr. Norwitz is a Dartmouth College graduate who completed his Ph.D in metabolism at Oxford University before attending Harvard Medical School to complete his MD.\xa0\nDr. Norwitz is passionate about teaching and encourages everyone to join the growing camp of metabolic health enthusiasts who will be instrumental in changing the world. In today's conversation, we explore the complex and controversial world of non-nutritive sweeteners, covering several topics, including the effects of allulose on PCOS, metabolic medicine, and the research on how gut sensor cells impact our preference for sugar over sweeteners. We look into studies on sucralose, commonly known as Splenda, and Dr. Norwitz shares insights from his Oreo LDL reduction experiment. We also touch on our human tendency toward simplicity and confirmation bias, the importance of bio-individuality, and the concept of N=1 medicine.\nDr. Norwitz is committed to remaining curious. He will return to the podcast later this year to share more about the research on metabolic health, muscle, and metabolism. I know you will love this discussion, so stay tuned for more.\n\nIN THIS EPISODE YOU WILL LEARN:\n\nHow the different molecules that exist within various types of non-nutritive sweeteners impact our biology\n\nDr. Norwitz explains how his view on non-nutritive sweeteners has shifted over time.\n\nWhy is allulose such a unique non-nutritive sweetener?\n\nHow the brain can distinguish between different sweetener molecules, and why that can drive changes in behavior\xa0\xa0\n\nDr. Norwitz explains how the hypothesis that sucralose may cause insulin resistance, was proven incorrect.\n\nWhy some non-nutritive sweeteners may be more problematic than others\n\nDr. Norwitz shares his approach to creating engaging social media content and discusses his famous Oreo versus statin experiments.\n\nWhy Dr. Norwitz believes that there should be more studies on lean mass hyper-responders\n\nHow dietary changes affect LDL cholesterol levels\n\nWhat is N=1 medicine?\n\n\nConnect with Cynthia Thurlow\xa0\xa0\n\nFollow on Twitter\n\n\nInstagram\n\nLinkedIn\n\nCheck out Cynthia\u2019s website\n\n\nSubmit your questions to support@cynthiathurlow.com\n\n\n\nConnect with Dr. Nick Norwitz\n\nX/Twitter\n\nYouTube\n\nInstagram\n\nLinkedIn\n\nThreads\n\nFaceBook\n\nWeekly Newsletter