Investigating the ubiquitin proteasome system

Published: Aug. 16, 2021, midnight

In today\u2019s podcast Professor Selina Wray from University College London, meets four early career researchers, who know a great deal about the brain, human iPSC derived cells and the ubiquitin-proteasome pathway (not that isn\u2019t a new type of electric car).\n\nWe\u2019ll be discussing their research, discovering more about super resolution microscopy, and how they\u2019re researching the ubiquitin proteasome system, and its connection to dementia.\n\nWe\u2019re delighted to welcome our guests:\n\nPhD Students Liina Sirvio, Katiuska Daniela Pulgar Prieto from the UK Dementia Research Institute at Imperial College London. Georgie Lines, PhD Student from University College London and Dr Emma Mee Haynes a Postdoctoral Research Associate also from the UK Dementia Research Institute at Imperial College London.\n\nWhat is the purpose of ubiquitin proteasome system?\n\nIn eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development.\n\nYou can find out more about our guests, and access a full transcript of this podcast on our website at:\n\nhttps://www.dementiaresearcher.nihr.ac.uk/podcast\n\n_________________________\n\nFinally, please review, like, and share our podcast - and don't forget to subscribe to ensure you never miss an episode.\n\nRegister on our website to receive your weekly bulletin, and to access more great content \u2013 blogs, science, career support + much more\n\nhttps://www.dementiaresearcher.nihr.ac.uk\n\nThis podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support.