Talking Rare: Epidemiology and Pathogenesis of APOL1-Mediated Kidney Disease
Host: Martin Pollak, MD
\n\n Guest: Susanne Nicholas, MD, MPH, PhD
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End-stage kidney disease (ESKD) is at least 3x higher among African Americans compared to Americans of European descent. Carriers of APOL1 variants with chronic kidney disease (CKD) are associated with more rapid disease progression and an increased risk of kidney failure. Join Drs. Martin Pollak and Susanne Nicholas as they discuss the epidemiology and possible mechanisms of APOL1 kidney disease, as well as recent clinical evidence for therapies in development that can potentially prevent rapid disease progression.