12- The Wnt Signalling Network
Building on our discussion of both signalling pathways and G-protein coupled receptors from a few weeks ago, this week we\u2019re going to discuss the Wnt signalling pathway- a pathway which is crucial in aspects of development and can have widespread impacts on the cell. It all sounds rather intimidating, but there\u2019s actually surprisingly few steps involved in this pathway- and we\u2019re only going to be focusing on one part of the signalling network, which makes life a lot less complicated!
\nSources for this episode: 1) Alberts, Johnson, Lewis, Raff, Roberts, and Walter (2008), Molecular Biology of the Cell, Fifth Edition, p.948- 950. Abingdon: Garland Science, Taylor and Francis Group LLC. 2) Janda, C. Y., Waghray, D., Levin, A. M., Thomas, C. and Garcia, K. C. (2012), Structural basis of Wnt recognition by Frizzled. Science 337: 59- 63. 3) Author unknown, National Center for Biotechnology Information (2020), PubChem Compound Summary for CID 445638, Palmitoleic acid (online) [Accessed 29/11/2020].