10- The Lamellipodium
As discussed in previous episodes, the actin cytoskeleton is vital to allow cells to move. But what about the specifics? In this episode, we\u2019re going to be dissecting the lamellipodium- a meshwork actin structure that some cells use to move.
\nSources for this episode: 1) Alberts, Johnson, Lewis, Raff, Roberts, and Walter (2008), Molecular Biology of the Cell, Fifth Edition. Abingdon: Garland Science, Taylor and Francis Group LLC. 2) Berro, Michelot, Blanchoin, Kovar and Martiel (2007), Attachment Conditions Control Actin Filament Buckling and the Production of Forces. Biophysical Journal 92(7): 2546- 2558. 3) Kiuchi, Ohashi, Kurita and Mizuno (2007), Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers. The Journal of Cell Biology 177(3): 465- 476. 4) \u2018Mechanobiology Institute, Singapore\u2019, YouTube (2013), Arp2/3 complex mediated actin nucleation (online) [Accessed 23/11/2020].