Summary of the May 5, 2015 issue, including articles on low-molecular-weight heparin for recurrent pregnancy loss, type 2 diabetes and obesity, sofosbuvir-based regimens for hepatitis C virus, fecal microbiota transplantation for Clostridium difficile infection, and high-value care education, as well as commentaries on opioid addiction, the chronic fatigue syndrome, and measles.